enow.com Web Search

Search results

  1. Results from the WOW.Com Content Network
  2. Heck reaction - Wikipedia

    en.wikipedia.org/wiki/Heck_reaction

    This reaction was the first example of a carbon-carbon bond-forming reaction that followed a Pd(0)/Pd(II) catalytic cycle, the same catalytic cycle that is seen in other Pd(0)-catalyzed cross-coupling reactions. The Heck reaction is a way to substitute alkenes.

  3. Intramolecular Heck reaction - Wikipedia

    en.wikipedia.org/wiki/Intramolecular_Heck_reaction

    Intramolecular Heck reactions have been employed for the construction of complex natural products. An example is the late-stage, macrocyclic ring closure in the total synthesis of the cytotoxic natural product (–)-Mandelalide A. [19] In another example a fully intramolecular tandem Heck reaction is used in a synthesis of (–)-scopadulcic acid.

  4. Richard F. Heck - Wikipedia

    en.wikipedia.org/wiki/Richard_F._Heck

    Richard Frederick Heck (August 15, 1931 – October 9, 2015) was an American chemist noted for the discovery and development of the Heck reaction, which uses palladium to catalyze organic chemical reactions that couple aryl halides with alkenes. The analgesic naproxen is an example of a compound that is prepared industrially using the Heck ...

  5. Heterogeneous metal catalyzed cross-coupling - Wikipedia

    en.wikipedia.org/wiki/Heterogeneous_metal...

    A 2021 survey of heterogeneous metal catalyzed cross-couplings in the fine chemical industry reported, out of 22 examples, 19 Suzuki or Heck reactions, which included only 2 examples with N-basic heterocycles, and only 4 examples with a singly-ortho-substituted electrophile (representative example in Scheme 1). [1]

  6. Cross-coupling reaction - Wikipedia

    en.wikipedia.org/wiki/Cross-coupling_reaction

    Often cross-coupling reactions require metal catalysts. One important reaction type is this: R−M + R'−X → R−R' + MX (R, R' = organic fragments, usually aryl; M = main group center such as Li or MgX; X = halide) These reactions are used to form carbon–carbon bonds but also carbon-heteroatom bonds.

  7. Catalytic cycle - Wikipedia

    en.wikipedia.org/wiki/Catalytic_cycle

    Articles on the Monsanto process, the Wacker process, and the Heck reaction show catalytic cycles. Catalytic cycle for conversion of A and B into C. A catalytic cycle is not necessarily a full reaction mechanism. For example, it may be that the intermediates have been detected, but it is not known by which mechanisms the actual elementary ...

  8. Coupling reaction - Wikipedia

    en.wikipedia.org/wiki/Coupling_reaction

    The most common type of coupling reaction is the cross coupling reaction. [1] [2] [3] Richard F. Heck, Ei-ichi Negishi, and Akira Suzuki were awarded the 2010 Nobel Prize in Chemistry for developing palladium-catalyzed cross coupling reactions. [4] [5] Broadly speaking, two types of coupling reactions are recognized:

  9. Vinylation - Wikipedia

    en.wikipedia.org/wiki/Vinylation

    The Heck reaction couples an unsaturated halide with an alkene. Base and a palladium catalyst are required. This reaction is a way to substitute alkenes. [4] [5] The Heck reaction in the production of Naproxen.