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  2. How marijuana impacts pain, sleep, anxiety and more ... - AOL

    www.aol.com/marijuana-impacts-pain-sleep-anxiety...

    Here’s where science currently stands on the use of marijuana for pain, sleep, anxiety, muscle spasms and other ailments — the results may surprise you. How marijuana impacts pain, sleep ...

  3. More than 20% of older adults have used pot in the past year ...

    www.aol.com/lifestyle/more-20-older-adults-used...

    Most people 50 and older who use cannabis do so at least once a month, saying it helps them sleep and eases pain, a new survey found. More than 20% of older adults have used pot in the past year ...

  4. Effects of cannabis - Wikipedia

    en.wikipedia.org/wiki/Effects_of_cannabis

    In dogs, the minimum lethal dose of THC is over 3000 mg/kg. [20] According to The Merck Index , [ 21 ] the LD 50 of THC (the dose which causes the death of 50% of individuals) is 1270 mg/kg for male rats and 730 mg/kg for female rats from oral consumption in sesame oil, and 42 mg/kg for rats from inhalation.

  5. Brotizolam - Wikipedia

    en.wikipedia.org/wiki/Brotizolam

    Brotizolam is a highly potent and short-acting hypnotic, with a typical dose ranging from 0.125 to 0.25 milligrams, which is rapidly eliminated with an average half-life of 4.4 hours (range 3.6–7.9 hours). [8] It was patented in 1974 [9] and came into medical use in 1984. [10] Brotizolam is not approved for sale in the UK, United States or ...

  6. Medical cannabis - Wikipedia

    en.wikipedia.org/wiki/Medical_cannabis

    The number of active chemicals in cannabis is one reason why treatment with cannabis is difficult to classify and study. [ 15 ] A 2014 review stated that the variations in ratio of CBD-to-THC in botanical and pharmaceutical preparations determines the therapeutic vs psychoactive effects (CBD attenuates THC's psychoactive effects [ 16 ] ) of ...

  7. Long-term effects of cannabis - Wikipedia

    en.wikipedia.org/wiki/Long-term_effects_of_cannabis

    Average score - positive symptoms Follow up: 12 months: On average, people receiving cannabis reduction therapy scored lower than people treated with treatment as usual but there was no clear difference between groups. This finding is based on data of moderate quality. MD 0.3 lower (2.55 lower to 1.95 higher)* Moderate Quality of life

  8. Recreational drug use - Wikipedia

    en.wikipedia.org/wiki/Recreational_drug_use

    Despite acknowledgement that drug use was greatly growing among America's youth during the late 1960s, surveys have suggested that only as much as 4% of the American population had ever smoked marijuana by 1969. By 1972, however, that number would increase to 12%. That number would then double by 1977. [47]

  9. Cannabis use disorder - Wikipedia

    en.wikipedia.org/wiki/Cannabis_use_disorder

    Cannabis use disorder (CUD), also known as cannabis addiction or marijuana addiction, is a psychiatric disorder defined in the fifth revision of the Diagnostic and Statistical Manual of Mental Disorders and ICD-10 as the continued use of cannabis despite clinically significant impairment.