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The first modern epinephrine autoinjector, the EpiPen, was invented in the mid-1970s at Survival Technology in Bethesda, Maryland, US by Sheldon Kaplan [11] [12] and was first approved for marketing by the FDA in 1987. [13] One of the people who helped in making the EpiPen was Richard B. Toren.
[14] [15] Epinephrine does this through its effects on alpha and beta receptors. [15] It is found in many animals and some single-celled organisms, [16] [17] but the medication is produced synthetically and is not harvested from animals. [18] Jōkichi Takamine first isolated epinephrine in 1901, and it came into medical use in 1905.
Adrenaline, also known as epinephrine, is a hormone and medication [10] [11] which is involved in regulating visceral functions (e.g., respiration). [10] [12] It appears as a white microcrystalline granule. [13]
Maropitant (INN; [3] brand name: Cerenia, used as maropitant citrate , is a neurokinin-1 (NK 1) receptor antagonist developed by Zoetis specifically for the treatment of motion sickness and vomiting in dogs. It was approved by the FDA in 2007, for use in dogs [4] [5] and in 2012, for cats. [6]
What is a needle-free EpiPen alternative? Neffy is a nasal spray that’s designed to be used in place of an EpiPen to treat people who are experiencing a severe allergic reaction.
Pfizer’s EpiPens may have set consumers back $600, but it’s now costing the drugmaker a whole lot more. Pfizer has agreed to pay $345 million to resolve claims by consumers who alleged they ...
Christopher Wren performed the earliest confirmed experiments with crude hypodermic needles, performing intravenous injection into dogs in 1656. [7] These experiments consisted of using animal bladders (as the syringe) and goose quills (as the needle) to administer drugs such as opium intravenously to dogs. Wren and others' main interest was to ...
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