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Trials in emergency department settings support the use of ondansetron to abort vomiting episodes associated with gastroenteritis and dehydration. [20] A randomized controlled trial using a single dose of oral ondansetron in children with presumably viral gastroenteritis found it to be highly effective in stopping vomiting and increasing the effectiveness of oral rehydration therapy, thereby ...
As many as 39% of the children had resolution of symptoms immediately or within weeks of the diagnosis. Vomiting had resolved at the time of follow-up in 61% of the sample. Many children, including those in the remitted group, continued to have somatic symptoms such as headaches (in 42%) and abdominal pain (in 37%). [18]
During an acute FPIES episode, if symptoms are mild (1-2 vomiting episodes), ondansetron or infacol may be given to control vomiting in children over 6 months of age, along with oral rehydration. If vomiting persists or if a child has more severe symptoms (i.e., lethargy, pallor, hypotonia), then the child should be taken to an emergency room ...
Ondansetron was approved by the U.S. Food and Drug Administration in 1991, and has since become available in several other countries, including the UK, Ireland, Australia, Canada, France and Brazil. As of 2008, ondansetron and granisetron are the only 5-HT 3 antagonists available as a generic drug in the United States. Ondansetron may be given ...
Signs and symptoms usually begin 12–72 hours after contracting the infectious agent. [15] If due to a virus, the condition usually resolves within one week. [18] Some viral infections also involve fever, fatigue, headache and muscle pain. [18] If the stool is bloody, the cause is less likely to be viral [18] and more likely to be bacterial. [19]
Medications include ondansetron, granisetron, and dolasetron. Anticholinergics can be used as a long-acting patch placed behind the patient's ear. Adverse effects include dry mouth and blurry vision. Care must be taken when handling the patch, as transfer of medication to the eye can induce pupillary dilation. Avoid use in elderly patients.
The signs and symptoms of Serotonin Syndrome include: Agitation or restlessness. Insomnia. Dilated pupils. Loss of muscle coordination or twitching muscles. Muscle rigidity. Tremor. Heavy sweating ...
Prochlorperazine, dimenhydrinate, ondansetron (sold under the brand-name Zofran) or corticosteroids may be used if these are not effective. [3] [4] Hospitalization may be required due to the severe symptoms associated. [9] [3] Psychotherapy may improve outcomes. [3] Evidence for acupressure is poor. [3]
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