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Triethylenetetramine (TETA and trien), also known as trientine when used medically, is an organic compound with the formula [CH 2 NHCH 2 CH 2 NH 2] 2. The pure free base is a colorless oily liquid, but, like many amines , older samples assume a yellowish color due to impurities resulting from air oxidation .
The reactivity and uses of TEPA are similar to those for the related ethylene amines ethylenediamine and diethylenetriamine and triethylenetetramine. It is primarily used as a curing agent or hardener in epoxy chemistry. This can be on its own or reacted with tall oil fatty acid (TOFA) and its dimer to make an amidoamine. [2]
Tren is a common impurity in the more common triethylenetetramine ("trien"). As a trifunctional amine, tren forms a triisocyanate when derivatized with COCl 2. TREN is known to react fast in the presence of (aromatic) aldehydes to form an imine. During this process, water is formed, making it a condensation reaction.
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Its manufacturing facilities are located in Israel, North America, Europe, Australia, and South America. The company is a member of the Pharmaceutical Research and Manufacturers of America (PhRMA). [4] [5] Teva Pharmaceuticals is the largest generic drug manufacturer in the world. Overall, Teva is the 18th largest pharmaceutical company in the ...
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Triethylenetetramine ("trien") Hexamethylenetetramine (hexamine) Tetramethylenedisulfotetramine (TETS), a rodenticide banned in most countries; Tetramine is also used as a synonym for the tetramethylammonium cation.