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This page provides supplementary chemical data on Cocaine in free base form. More commonly available "powder cocaine" is a hydrochloride salt whose properties will differ. Material Safety Data Sheet
Chemical structure of cocaine. The biosynthesis of cocaine has long attracted the attention of biochemists and organic chemists. This interest is partly motivated by the strong physiological effects of cocaine, but a further incentive was the unusual bicyclic structure of the molecule. The biosynthesis can be viewed as occurring in two phases ...
Trituration of the free base from cocaine hydrochloride (or "cooking") is done by dissolving the cocaine hydrochloride in water over constant heat, while simultaneously adding a base (such as baking soda) to form the free base cocaine. The free base of cocaine forms a solid "rock", pieces of which can be smoked directly (crack cocaine). [4]
Cocaine stimulates the mesolimbic pathway in the brain. [15] Mental effects may include an intense feeling of happiness, sexual arousal, loss of contact with reality, or agitation. [12] Physical effects may include a fast heart rate, sweating, and dilated pupils. [12] High doses can result in high blood pressure or high body temperature. [16]
A cocaine analogue is an (usually) artificial construct of a novel chemical compound from (often the starting point of natural) cocaine's molecular structure, with the result product sufficiently similar to cocaine to display similarity in, but alteration to, its chemical function.
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Methylecgonidine (anhydromethylecgonine; anhydroecgonine methyl ester; AEME) is a chemical intermediate derived from ecgonine or cocaine.. Methylecgonidine is a pyrolysis product formed when crack cocaine is smoked, making this substance a useful biomarker to specifically test for use of crack cocaine, as opposed to powder cocaine which does not form methylecgonidine as a metabolite. [1]
Mexican authorities seized more than seven tons of suspected cocaine in two separate raids in the Pacific Ocean, the country's navy said, and dramatic video captured the high-speed chases on the ...