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Varenicline, sold under the brand names Chantix and Champix among others, is a medication used for smoking cessation [5] [7] and for the treatment of dry eye syndrome. [ 6 ] [ 8 ] It is a nicotinic acetylcholine receptor partial agonist .
Schwyzer states that Raphael Holinshed's 1577 Chronicles of England, Scotland, and Ireland is the first work of historiography to deal with the British Isles in particular; "To the best of my knowledge, no book published in England before 1577 specified in its title a scope at once inclusive of and restricted to England, Scotland, and Ireland".
The largest town on the peninsula is Cherbourg-en-Cotentin, a major cross-channel port on the north coast, with a population of approximately 120,000. The population of the peninsula is about 250,000. The western coast of the peninsula, known as the Côte des Îles ("Islands Coast"), faces the Channel Islands
Britain in Bloom divides England into 12 regions, bearing a mixture of government regions with some altered names. It also includes Cumbria , Thames-and-Chilterns ( Berkshire , Buckinghamshire and Oxfordshire ) and part of south east and south west as South-and-South-West.
Lancashire is a county of England, in the northwest of the country. The county did not exist in 1086, for the Domesday Book, and was apparently first created in 1182, [1] making it one of the youngest of the traditional counties. The historic county consisted of two separate parts. The main part runs along the northwestern coast of England.
The island of Thanet is mentioned as Tonetic (c. AD 150; the TON- of this form was misread as TOΛI-, hence it appears as Toliatis in the surviving manuscripts of Ptolemy); Tanat's, [2] Athanatos and Thanatos (in various copies of 3rd C AD, Solinus); [3] Tanatos (AD 731); Tenid in 679 [2] and Tenet (e.g. charters of AD 679, 689 and thereafter); and the Old Welsh forms Tanet and Danet, found in ...
The village pub is The Jolly Farmer, located in what was in 1672 part of a pair of farm dwellings, and originally registered as a public house in November 1738 by Lazarus Haywood under the name "Jolly Farmers". It was leased to its first tenant Keeper, Samuel Packer (a boot and shoe maker from Ramsgate) in March 1739.
England has 4,422 km (2,748 mi) of coastline, [13] much less than the deeply indented Scottish coastline. The English coastline varies a great deal by the seas and regions it borders. The North Sea coast of England is mainly flat and sandy with many dunes and is similar to coastlines across the sea in the Netherlands. The English North Sea ...