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CSF has also been seen to drain into lymphatic vessels, [29] particularly those surrounding the nose via drainage along the olfactory nerve through the cribriform plate. The pathway and extent are currently not known, [1] but may involve CSF flow along some cranial nerves and be more prominent in the neonate. [3]
MRI showing flow of CSF The ventricles are filled with cerebrospinal fluid (CSF) which bathes and cushions the brain and spinal cord within their bony confines. CSF is produced by modified ependymal cells of the choroid plexus found in all components of the ventricular system except for the cerebral aqueduct and the posterior and anterior horns ...
CSF flow can be used in diagnosing and treating aqueduct stenosis, normal pressure hydrocephalus, and Chiari malformation. [6] Aqueduct stenosis is the narrowing of the aqueduct of Sylvius which blocks the flow of CSF, causing fluid buildup in the brain called hydrocephalus.
The blood–cerebrospinal fluid barrier (BCSFB) is a fluid–brain barrier that is composed of a pair of membranes that separate blood from CSF at the capillary level and CSF from brain tissue. [14] The blood–CSF boundary at the choroid plexus is a membrane composed of epithelial cells and tight junctions that link them. [14]
Studies in 1985 indicated that cerebrospinal fluid and interstitial fluid may flow along specific anatomical pathways within the brain, with CSF moving into the brain along the outside of blood vessels; such 'paravascular channels' were possibly analogous to peripheral lymph vessels, facilitating the clearance of interstitial wastes from the brain.
Radionuclide cisternography may be used to diagnose a spinal cerebrospinal fluid leak. CSF pressure is measured and imaged over 24 hours. [2] A radionuclide (radioisotope) is injected by lumbar puncture (spinal tap) into the cerebral spinal fluid to determine if there is abnormal CSF flow within the brain and spinal canal which can be altered by hydrocephalus, Arnold–Chiari malformation ...
It receives CSF from the fourth ventricle via the median aperture (foramen of Magendie). The cisterna magna contains: The vertebral artery and the origin of the posterior inferior cerebellar artery (PICA) The ninth (IX), tenth (X), eleventh (XI) and twelfth (XII) cranial nerves; Pontine cistern. Surrounds the ventral aspect of the pons
CSF circulates in the subarachnoid space (between arachnoid and pia mater). Cerebrospinal fluid is produced by the choroid plexus (inside the ventricles of the brain, which are in direct communication with the subarachnoid space so the CSF can flow freely through the nervous system). Cerebrospinal fluid is a transparent, colourless fluid and it ...