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In 2013, the drug was approved for use in the United States by the Food and Drug Administration (FDA) for long-term maintenance treatment of airflow obstruction in people with COPD, including chronic bronchitis and emphysema, [6] and the European Medicines Agency approved it as a second-line therapy for the treatment of COPD and asthma. [7]
The combination fluticasone furoate/umeclidinium bromide/vilanterol product is approved by the US Food and Drug Administration with an indication for the maintenance treatment of a chronic lung problem called chronic obstructive pulmonary disease (COPD) in adults who (1) have already tried fluticasone furoate/vilanterol (brand name Breo Ellipta) but are still experiencing symptoms of airway ...
A dry-powder inhaler (DPI) is a device that delivers medication to the lungs in the form of a dry powder. DPIs are commonly used to treat respiratory diseases such as asthma, bronchitis, emphysema and COPD although DPIs (such as inhalable insulin) have also been used in the treatment of diabetes mellitus. [1]
COPD is generally irreversible although lung function can partially recover if the patient stops smoking. Smoking cessation is an essential aspect of treatment. [9] Pulmonary rehabilitation programmes involve intensive exercise training combined with education and are effective in improving shortness of breath.
Most commonly emphysema refers to the permanent enlargement of air spaces in the lungs, [5] [6] and is also known as pulmonary emphysema. Emphysema is a lower respiratory tract disease, [ 7 ] characterised by enlarged air-filled spaces in the lungs , that can vary in size and may be very large.
Chronic obstructive pulmonary disease (COPD), is a progressive lung disease. The term COPD includes two main conditions: (1) emphysema and (2) chronic bronchitis. Emphysema develops when the walls of alveoli are destroyed, forming fewer larger alveoli. Chronic bronchitis is triggered by repeated or constant irritation and inflammation in the ...
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