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The most common form of colon cancer is adenocarcinoma, constituting between 95% [2] and 98% [3] of all cases of colorectal cancer. Other, rarer types include lymphoma, adenosquamous and squamous cell carcinoma. Some subtypes have been found to be more aggressive. [4]
In histology, a signet ring cell is a cell with a large vacuole. The malignant type is seen predominantly in carcinomas. Signet ring cells are most frequently associated with stomach cancer, [1] but can arise from any number of tissues including the prostate, [2] bladder, gallbladder, [3] breast, colon, [4] ovarian stroma and testis. [5]
HGSC is distinct from low-grade serous carcinoma (LGSC) which arises from ovarian tissue, is less aggressive and is present in stage I ovarian cancer where tumours are localised to the ovary. Although originally thought to arise from the squamous epithelial cell layer covering the ovary, HGSC is now thought to originate in the Fallopian tube ...
Serous ovarian cancer is the most common type of epithelial ovarian cancer and it accounts for about two-thirds of cases of epithelial ovarian cancer. [28] Low-grade serous carcinoma is less aggressive than high-grade serous carcinomas, though it does not typically respond well to chemotherapy or hormonal treatments. [ 28 ]
Krukenberg tumors often come to the attention when they cause abdominal or pelvic pain, bloating, ascites, or pain during sexual intercourse.Krukenberg tumors can occasionally provoke a reaction of the ovarian stroma which leads to hormone production, that results in vaginal bleeding, a change in menstrual habits, or hirsutism, [3] or occasionally virilization [4] as a main symptom.
Histologic specimen being placed on the stage of an optical microscope Human lung tissue stained with hematoxylin and eosin as seen under a microscope. Histology, [help 1] also known as microscopic anatomy or microanatomy, [1] is the branch of biology that studies the microscopic anatomy of biological tissues.
Theca cells are a group of endocrine cells in the ovary made up of connective tissue surrounding the follicle. They have many diverse functions, including promoting folliculogenesis and recruitment of a single follicle during ovulation. [2] Theca cells and granulosa cells together form the stroma of the ovary.
Grading in cancer is distinguished from staging, which is a measure of the extent to which the cancer has spread. Pathology grading systems classify the microscopic cell appearance abnormality and deviations in their rate of growth with the goal of predicting developments at tissue level (see also the 4 major histological changes in dysplasia).