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  2. Direct factor Xa inhibitors - Wikipedia

    en.wikipedia.org/wiki/Direct_factor_Xa_inhibitors

    Antistasin, the first discovered naturally occurring direct Xa inhibitor Rivaroxaban, the first synthetic direct Xa inhibitor marketed as a drug Prior to the introduction of direct factor Xa inhibitors, vitamin K antagonists such as warfarin were the only oral anticoagulants for over 60 years, and together with heparin have been the main blood ...

  3. Rivaroxaban - Wikipedia

    en.wikipedia.org/wiki/Rivaroxaban

    Rivaroxaban, sold under the brand name Xarelto among others, is an anticoagulant medication (blood thinner) used to treat and prevent blood clots. [8] Specifically it is used to treat deep vein thrombosis and pulmonary emboli and prevent blood clots in atrial fibrillation and following hip or knee surgery. [8] It is taken by mouth. [8]

  4. Diarrhea - Wikipedia

    en.wikipedia.org/wiki/Diarrhea

    Diarrhea is defined by the World Health Organization as having three or more loose or liquid stools per day, or as having more stools than is normal for that person. [2] Acute diarrhea is defined as an abnormally frequent discharge of semisolid or fluid fecal matter from the bowel, lasting less than 14 days, by World Gastroenterology ...

  5. Here's What 'Diarrhea' Actually Means and When You Should ...

    www.aol.com/lifestyle/heres-diarrhea-actually...

    Usually, your diarrhea will go away once you stop taking medications. How To Treat Diarrhea at Home. Most of the time, diarrhea can be treated at home, without the need to involve your health care ...

  6. This New Supplement May Help Alleviate Joint Pain And ... - AOL

    www.aol.com/supplement-may-help-alleviate-joint...

    Some medications may interact with MSM, including drugs to treat or prevent blood clots, like warfarin, enoxaparin, dalteparin, apixaban, dabigatran, and rivaroxaban, according to the Cleveland ...

  7. Discovery and development of direct Xa inhibitors - Wikipedia

    en.wikipedia.org/wiki/Discovery_and_development...

    Rivaroxaban. During the SAR development of rivaroxaban, researchers realized that adding a 5-chlorothiophene-2-carboxamide group to the oxazolidonine core could increase the potency by 200 fold, which had previously been too weak for medical use. In addition to this discovery, a clear preference for the (S)-configuration was confirmed.

  8. Antidiarrheal - Wikipedia

    en.wikipedia.org/wiki/Antidiarrheal

    Electrolyte solutions, while not true antidiarrheals, are used to replace lost fluids and salts in acute cases.; Bulking agents like methylcellulose, guar gum or plant fibre (bran, sterculia, isabgol, etc.) are used for diarrhoea in functional bowel disease and to control ileostomy output.

  9. Gastrointestinal Outbreak Sickens 90 on Royal Caribbean's ...

    www.aol.com/gastrointestinal-outbreak-sickens-90...

    Over 90 people aboard a Royal Caribbean International cruise are sick with gastrointestinal illnesses, causing vomiting and diarrhea as staff members try to pinpoint the source of the outbreak ...

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