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Infectious mononucleosis (IM, mono), also known as glandular fever, is an infection usually caused by the Epstein–Barr virus (EBV). [2] [3] Most people are infected by the virus as children, when the disease produces few or no symptoms. [2] In young adults, the disease often results in fever, sore throat, enlarged lymph nodes in the neck, and ...
Many children who become infected with EBV display no symptoms or the symptoms are indistinguishable from the other mild, brief illnesses of childhood. [21] When infection occurs during adolescence or young adulthood, it causes infectious mononucleosis 35 to 50% of the time. [22] EBV infects B cells of the immune system and epithelial cells.
The disease develops as a complication or progression of either Epstein–Barr virus-positive infectious mononucleosis (EPV+ IM) or chronic active Epstein–Barr virus infection (CAEBV)., [1] that is, as a worsening of the signs/symptoms some three weeks after the onset of an EBV+ IM-like disease or an any time during the course of CAEBV.
Women conversely are at higher risk for developing autoimmune disease, but are more protected from infectious disease than men. Women have a greater number of circulating antibodies than do men, [46] which has implications for their development of autoimmune disease, as well as their increased resistance to infectious disease.
It will generally not be positive during the 4–6 week incubation period before the onset of symptoms. The highest amount of heterophile antibodies occurs 2 to 5 weeks after the onset of symptoms. [9] If positive, it will remain so for at least six weeks. [10] An elevated heterophile antibody level may persist up to 1 year. [9]
This "crash" can last from hours or days to several months. Further common symptoms include dizziness or faintness when upright and pain. [3] [10] The cause of the disease is unknown. [11] ME/CFS often starts after an infection, such as mononucleosis. [12] It can run in families, but no genes that contribute to ME/CFS have been confirmed. [13]
The main symptoms of COVID-19 haven’t really changed over time. The CDC lists the following as possible signs of the virus: Fever or chills ... How long the symptoms last depends on the severity ...
Joint-area discoloration, dactylitis, nail changes, and enthesitis, are common symptoms of psoriatic arthritis that distinguish it from other forms of arthritis. Unlike other types of inflammatory arthritis, which typically affect women more than men, psoriatic arthritis has no gender preference.