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The G4 virus, also known as the "G4 swine flu virus" (G4) and "G4 EA H1N1", is a swine influenza virus strain discovered in China. [68] The virus is a variant genotype 4 (G4) Eurasian avian-like (EA) H1N1 virus that mainly affects pigs, but there is some evidence of it infecting people. [ 68 ]
The virus is a novel strain of the influenza virus, [2] for which existing vaccines against seasonal flu provided no protection. A study at the U.S. Centers for Disease Control and Prevention (CDC) published in May 2009 found that children had no preexisting immunity to the new strain but that adults, particularly those over 60, had some degree of immunity.
The 2009 swine flu pandemic, caused by the H1N1/swine flu/influenza virus and declared by the World Health Organization (WHO) from June 2009 to August 2010, was the third recent flu pandemic involving the H1N1 virus (the first being the 1918–1920 Spanish flu pandemic and the second being the 1977 Russian flu).
It was caused by an H1N1 flu strain which highly resembled a virus strain circulating worldwide from 1946 to 1957. [ 1 ] [ 2 ] [ 5 ] [ 6 ] Genetic analysis and several unusual characteristics of the 1977 Russian flu have prompted many researchers to say that the virus was released to the public through a laboratory accident, [ 4 ] [ 5 ] [ 7 ...
Pigs usually recover within 3–7 days after symptoms appear. Prevention and control measures include inactivated vaccines and culling infected herds. Influenza A virus subtypes H1N1, H1N2, and H3N2 are usually responsible for swine flu. [92] Some influenza A viruses can be transmitted via aerosols from pigs to humans and vice versa. [1]
The 2015 Indian swine flu outbreak refers to an outbreak of the H1N1 virus [1] in India, during early 2015. The states of Gujarat and Rajasthan were the worst affected. [2] [3] [4] India had reported 937 cases and 218 deaths from swine flu in the year 2014. By mid-February 2015, the reported cases and deaths in 2015 had surpassed the previous ...
Influenza A virus structure. The influenzavirus virion is pleomorphic; the viral envelope can occur in spherical and filamentous forms. In general, the virus's morphology is ellipsoidal with particles 100–120 nm in diameter, or filamentous with particles 80–100 nm in diameter and up to 20 μm long. [5]
In the 21st century, a strain of H1N1 flu (since titled H1N1pdm09) which was antigenically very different from previous H1N1 strains, leading to a pandemic in 2009. Because of its close resemblance to some strains circulating in pigs, this became known as "Swine flu" [46] Influenza A virus continues to circulate and evolve in birds and pigs.