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Sildenafil Drug Interactions. A word on sildenafil drug interactions: Mixing antihypertensive prescription drugs (hypertension meds) with Viagra may cause low blood pressure. Since the medication ...
After further trials, sildenafil citrate was approved by the Food and Drug Administration (FDA) in 1998 as the active ingredient in brand name Viagra, now a very well-known drug for ED. For most ...
The Best ED Medication for Men: Pros & Cons of Top ED Pills. Over the last 25 years, (ED) medications like Viagra and Cialis have become common fixtures in bedrooms around the world.
Sildenafil's brand name, Viagra, is widely recognized in popular culture, and the drug's association with treating erectile dysfunction has led to its recreational use. [33] The reasons behind such use include the belief that the drug increases libido, improves sexual performance, [ 33 ] or permanently increases penis size. [ 34 ]
Chemical structure of sildenafil (Viagra), the prototypical PDE5 inhibitor. A phosphodiesterase type 5 inhibitor (PDE5 inhibitor) is a vasodilating drug that works by blocking the degradative action of cGMP-specific phosphodiesterase type 5 (PDE5) on cyclic GMP in the smooth muscle cells lining the blood vessels supplying various tissues.
Sildenafil is a prototype of PDE5 inhibitors that Pfizer launched as Viagra. It was approved by the Food and Drug Administration (FDA) in 1998 as the first oral medicine for erectile dysfunction. Later, in the year 2005, it was approved for the treatment of pulmonary arterial hypertension. [ 2 ]
Viagra’s main ingredient sildenafil is part of a class of drugs referred to as PDE5 inhibitors, which (unlike non-prescription supplements) are approved by the FDA for the treatment of ED.
Some authors recommend the use of sildenafil by mouth to replace the injectable drugs in cases of contraindications, although the efficacy of such medication is controversial. [45] Before the injection of the chosen drug, the flow pattern is monophasic, with low systolic velocities and an absence of diastolic flow.