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The most important factor that must be taken into account when designing any type of drug delivery device, and specifically ocular devices, is the release rate of a drug. As discussed previously, the deliver rate and kinetics associated with drugs to the eye can reach levels that are toxic to the eye or could even cause undesirable side effects.
Latanoprost, sold under the brand name Xalatan among others, is a medication used to treat increased pressure inside the eye (intraocular pressure). [5] This includes ocular hypertension and open-angle glaucoma. [5] Latanaprost is applied as eye drops to the eyes. [5] Onset of effects is usually within four hours, and they last for up to a day. [5]
Intravitreal injection is the method of administration of drugs into the eye by injection with a fine needle. The medication will be directly applied into the vitreous humor . [ 1 ] It is used to treat various eye diseases, such as age-related macular degeneration (AMD) , diabetic retinopathy , and infections inside the eye such as ...
Tropicamide, sold under the brand name Mydriacyl among others, is a medication used to dilate the pupil and help with examination of the eye. [3] Specifically it is used to help examine the back of the eye. [4] It is applied as eye drops. [3] Effects occur within 40 minutes and last for up to a day. [3]
Recommended duration of treatment is less than six days, [4] and in Switzerland not more than seven days (parenterally two days). [6] It is used by mouth, by nose, by injection into a vein or muscle, and as eye drops. [4] [5] Effects begin within an hour and last for up to eight hours. [4] Ketorolac also has antipyretic (fever-reducing ...
Side effects in less than 10% of people include other eye problems such as itching, foreign body sensation or dry eye, as headache or hyperpigmentation (darkening) of the skin around the eye. [4] Hyperpigmentation is an adverse effect of bimatoprost, [5] while the others are fairly common for eye drops in general.
Travoprost, sold under the brand name Travatan among others, is a medication used to treat high pressure inside the eye including glaucoma. [4] Specifically it is used for open angle glaucoma when other agents are not sufficient. [5] [4] It is used as an eye drop. [4] Effects generally occur within two hours. [4]
Onset of effects with the drops is typically within an hour and lasts for up to a day. [1] By mouth it is used for dry mouth as a result of Sjögren syndrome or radiation therapy. [9] Common side effects of the eye drops include irritation of the eye, increased tearing, headache, and blurry vision. [1]
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