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Phineas P. Gage (1823–1860) was an American railroad construction foreman remembered for his improbable: 19 survival of an accident in which a large iron rod was driven completely through his head, destroying much of his brain's left frontal lobe, and for that injury's reported effects on his personality and behavior over the remaining 12 years of his life—effects sufficiently ...
White matter is the tissue through which messages pass between different areas of grey matter within the central nervous system. The white matter is white because of the fatty substance (myelin) that surrounds the nerve fibers (axons). This myelin is found in almost all long nerve fibers, and acts as an electrical insulation.
A lobotomy (from Greek λοβός (lobos) 'lobe' and τομή (tomē) 'cut, slice') or leucotomy is a discredited form of neurosurgical treatment for psychiatric disorder or neurological disorder (e.g. epilepsy, depression) that involves severing connections in the brain's prefrontal cortex. [1]
Phineas Gage got an iron rod shot up through his skull, injuring his brain and his skull and blinding him in his left eye. His surgeon performed medical surgery on him that relieved the pressure in his skull which ultimately saved his life (King Henri II, if he had received a similar procedure, may have survived).
White matter fiber connections in DTI data are then drawn between these cortical regions and weighted by fractional anisotropy and strength of the connection. Such graphs have even been used to analyze the damage done to the famous traumatic brain injury patient Phineas Gage. [56]
A penetrating head injury, or open head injury, is a head injury in which the dura mater, the outer layer of the meninges, is breached. [1] Penetrating injury can be caused by high-velocity projectiles or objects of lower velocity such as knives, or bone fragments from a skull fracture that are driven into the brain.
Phineas Gage, who sustained a severe frontal lobe injury in 1848, has been called a case of dysexecutive syndrome. Gage's psychological changes are almost always exaggerated – of the symptoms listed, the only ones Gage can be said to have exhibited are "anger and frustration", slight memory impairment, and "difficulty in planning".
John Martyn Harlow (1819–1907) was an American physician primarily remembered for his attendance on brain-injury survivor Phineas Gage, and for his published reports on Gage's accident and subsequent history. Boston Herald, May 20, 1907. Harlow was born in Whitehall, New York on November 25, 1819 to Ransom and Annis Martyn Harlow. [1]