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Brimonidine/timolol, sold under the brand name Combigan among others, is a fixed-dose combination medication eye drop used for the treatment of glaucoma. [1] It is a combination of brimonidine (an α 2 adrenergic agonist ) and timolol (a β adrenergic blocker ).
Open-angle glaucoma (a condition where the aqueous humour, the watery fluid inside the eyeball, cannot drain away properly) and other causes of high pressure in the eye increase the risk of damage to the retina and the optic nerve (the nerve that sends signals from the eye to the brain). [4] This can result in serious vision loss and even ...
It is used as eye drops or applied to the skin. [4] [5] It is also available in the fixed-dose combination medication brimonidine/timolol along with timolol maleate. [6] Common side effects when used in the eyes include itchiness, redness, and a dry mouth. [4] Common side effects when used on the skin include redness, burning, and headaches. [5]
Apraclonidine (), also known under the brand name Iopidine, is a sympathomimetic used in glaucoma therapy. It is an α 2 adrenergic receptor agonist and a weak α 1 adrenergic receptor agonist.
[3] [5] As eye drops it is used to treat increased pressure inside the eye such as in ocular hypertension and glaucoma. [3] By mouth it is used for high blood pressure, chest pain due to insufficient blood flow to the heart, to prevent further complications after a heart attack, and to prevent migraines. [5] Common side effects with the drops ...
What Not To Use As A Substitute It's a shame that so many well-intentioned but misguided recipes encourage us to use milk curdled with lemon juice or vinegar as a replacement for buttermilk.