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The advent of the first low dead space syringe occurred with the creation of 1-ml syringes designed specifically for the administration of insulin. Then amongst the scare of HIV and rising concern of other communicable diseases to healthcare workers the creation of safety syringes occurred in 1988.
Injector pens remove some of the complications of syringes by allowing the pen to be "pushed" against the skin at a 90-degree angle (removing the need to inject at a proper angle as is the case with syringes), as well as by replacing a long, thin plunger of a syringe with a simple button which is depressed and held to inject the dose.
Insulin syringes are marked in insulin "units". Syringes for insulin users are designed for standard U-100 insulin. The dilution of insulin is such that 1 mL of insulin fluid has 100 standard "units" of insulin. [6] Since insulin vials are typically 10 mL, each vial has 1000 units. Insulin syringes are made specifically for self injections and ...
Insulin glargine differs from human insulin by replacing asparagine with glycine in position 21 of the A-chain and by carboxy-terminal extension of B-chain by 2 arginine residues. The arginine amino acids shift the isoelectric point from a pH of 5.4 to 6.7, making the molecule more soluble at an acidic pH and less soluble at physiological pH.
without (usually written with a bar on top of the s) sing. singulorum: of each SL, s.l. sub lingua: sublingually, under the tongue SOB shortness of breath sol. solutio: solution s.o.s., si op. sit si opus sit: if there is a need s.s., SS semisse: one-half [or] sliding scale mistaken for "55" or "1/2" SSI sliding scale insulin or sliding scale ...
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