enow.com Web Search

Search results

  1. Results from the WOW.Com Content Network
  2. Thyrotropin-releasing hormone - Wikipedia

    en.wikipedia.org/wiki/Thyrotropin-releasing_hormone

    The hypothalamic-pituitary-thyroid axis. TRH can be seen in green. TRH is synthesized within parvocellular neurons of the paraventricular nucleus of the hypothalamus. [2] It is translated as a 242-amino acid precursor polypeptide that contains 6 copies of the sequence -Gln-His-Pro-Gly-, with both ends of the sequence flanked by Lys-Arg or Arg-Arg sequences.

  3. TRH stimulation test - Wikipedia

    en.wikipedia.org/wiki/TRH_stimulation_test

    TRH-stimulation testing however continues to be useful for the differential diagnosis of secondary (pituitary disorder) and tertiary (hypothalamic disorder) hypothyroidism. Patients with these conditions appear to have physiologically inactive TSH in their circulation that is recognized by TSH assays to a degree such that they may yield ...

  4. Hypothalamic–pituitary–thyroid axis - Wikipedia

    en.wikipedia.org/wiki/Hypothalamic–pituitary...

    The TRH stimulates the anterior pituitary to produce thyroid-stimulating hormone (TSH). The TSH, in turn, stimulates the thyroid to produce thyroid hormone until levels in the blood return to normal. Thyroid hormone exerts negative feedback control over the hypothalamus as well as anterior pituitary, thus controlling the release of both TRH ...

  5. Thyrotropin-releasing hormone receptor - Wikipedia

    en.wikipedia.org/wiki/Thyrotropin-releasing...

    22045 Ensembl ENSG00000174417 ENSMUSG00000038760 UniProt P34981 P21761 RefSeq (mRNA) NM_003301 NM_013696 RefSeq (protein) NP_003292 NP_038724 Location (UCSC) Chr 8: 109.09 – 109.12 Mb Chr 15: 44.06 – 44.1 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Thyrotropin-releasing hormone receptor (TRHR) is a G protein-coupled receptor which binds thyrotropin-releasing hormone. The TRHR ...

  6. Paraventricular nucleus of hypothalamus - Wikipedia

    en.wikipedia.org/wiki/Paraventricular_nucleus_of...

    CRH and TRH are secreted into the hypophyseal portal system, and target different neurons in the anterior pituitary. Dysfunctions of the PVN can cause hypersomnia in mice. [ 2 ] In humans, the dysfunction of the PVN and the other nuclei around it can lead to drowsiness for up to 20 hours per day. [ 3 ]

  7. Thyroid-stimulating hormone - Wikipedia

    en.wikipedia.org/wiki/Thyroid-stimulating_hormone

    Thyroid-stimulating hormone (also known as thyrotropin, thyrotropic hormone, or abbreviated TSH) is a pituitary hormone that stimulates the thyroid gland to produce thyroxine (T 4), and then triiodothyronine (T 3) which stimulates the metabolism of almost every tissue in the body. [1]

  8. Thyroid function tests - Wikipedia

    en.wikipedia.org/wiki/Thyroid_function_tests

    Thyroid function tests (TFTs) is a collective term for blood tests used to check the function of the thyroid. [1] TFTs may be requested if a patient is thought to suffer from hyperthyroidism (overactive thyroid) or hypothyroidism (underactive thyroid), or to monitor the effectiveness of either thyroid-suppression or hormone replacement therapy.

  9. Thyrotropic cell - Wikipedia

    en.wikipedia.org/wiki/Thyrotropic_cell

    TRH stimulates the thyrotropic cells through the use of a phospholipase C second messenger system. [1] TRH binds to a class A G protein-coupled receptor on the surface of a thyrotropic cell, which is known as the thyrotropin-releasing hormone receptor (TRHR). Strong hydrogen bonding interactions stabilize the binding of TRH to TRHR.