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Bovine spongiform encephalopathy (BSE), commonly known as mad cow disease, is an incurable and invariably fatal neurodegenerative disease of cattle. [2] Symptoms include abnormal behavior, trouble walking, and weight loss. [1] Later in the course of the disease, the cow becomes unable to function normally. [1]
TSEs in non-human mammals include scrapie in sheep, bovine spongiform encephalopathy (BSE) in cattle – popularly known as "mad cow disease" – and chronic wasting disease (CWD) in deer and elk. The variant form of Creutzfeldt–Jakob disease in humans is caused by exposure to bovine spongiform encephalopathy prions. [4] [5] [6]
Atypical bovine spongiform encephalopathy , commonly known as mad cow disease, has been confirmed in a cow on a farm in Dumfries and Galloway. The Scottish government said precautionary movement ...
The first is that the disease originated through interspecific contamination from a closely related disease, scrapie. The possibility of interspecific transmission of scrapie has been proven experimentally, but the clinical and neuropathological disorders associated with the disease differ from those of bovine spongiform encephalopathy.
The United Kingdom was afflicted with an outbreak of bovine spongiform encephalopathy (BSE, also known as "mad cow disease"), and its human equivalent variant Creutzfeldt–Jakob disease (vCJD), in the 1980s and 1990s. Over four million head of cattle were slaughtered in an effort to contain the outbreak, and 178 people died after contracting ...
Dark green areas are countries that have confirmed human cases of variant Creutzfeldt–Jakob disease and light green are countries that have bovine spongiform encephalopathy cases. The Lancet in 2006 suggested that it may take more than 50 years for vCJD to develop, from their studies of kuru, a similar disease in Papua New Guinea. [54]
CJD is a cousin of bovine spongiform encephalopathy, commonly called mad cow disease. More than 250 growth hormone patients have been diagnosed with CJD worldwide.
The human prion disease variant Creutzfeldt–Jakob disease, however, is thought to be caused by a prion that typically infects cattle, causing bovine spongiform encephalopathy and is transmitted through infected meat. [83] All known prion diseases are untreatable and fatal. [9] [84] [85]