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  2. Causes of cancer - Wikipedia

    en.wikipedia.org/wiki/Causes_of_cancer

    A cancer syndrome or family cancer syndrome is a genetic disorder in which inherited genetic mutations in one or more genes predisposes the affected individuals to the development of cancers and may also cause the early onset of these cancers. Although cancer syndromes exhibit an increased risk of cancer, the risk varies.

  3. Cancer cell - Wikipedia

    en.wikipedia.org/wiki/Cancer_cell

    Although a DNA repair deficiency can predispose a cell lineage to develop cancer, increased (rather than decreased) expression of a repair capability may also emerge in the progression of cancer cell lineages, and this capability may be clinically important as reviewed by Lingg et al. [9] For instance, the DNA repair gene DMC1 encodes a protein ...

  4. Plant sources of anti-cancer agents - Wikipedia

    en.wikipedia.org/wiki/Plant_sources_of_anti...

    It has been argued that "the use of natural products has been the single most successful strategy in the discovery of novel medicines". [3] Plants need to defend themselves from attack by micro-organisms, in particular fungi, and they do this by producing anti-fungal chemicals that are toxic to fungi.

  5. Carcinogenesis - Wikipedia

    en.wikipedia.org/wiki/Carcinogenesis

    The central role of DNA damage and epigenetic defects in DNA repair genes in carcinogenesis. DNA damage is considered to be the primary cause of cancer. [17] More than 60,000 new naturally-occurring instances of DNA damage arise, on average, per human cell, per day, due to endogenous cellular processes (see article DNA damage (naturally occurring)).

  6. Radiation-induced cancer - Wikipedia

    en.wikipedia.org/wiki/Radiation-induced_cancer

    Radiation hormesis is the conjecture that a low level of ionizing radiation (i.e., near the level of Earth's natural background radiation) helps "immunize" cells against DNA damage from other causes (such as free radicals or larger doses of ionizing radiation), and decreases the risk of cancer. The theory proposes that such low levels activate ...

  7. Cancer - Wikipedia

    en.wikipedia.org/wiki/Cancer

    Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. [2] [7] These contrast with benign tumors, which do not spread. [7] Possible signs and symptoms include a lump, abnormal bleeding, prolonged cough, unexplained weight loss, and a change in bowel movements. [1]

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  9. Clonally transmissible cancer - Wikipedia

    en.wikipedia.org/wiki/Clonally_transmissible_cancer

    A transmissible cancer is a cancer cell or cluster of cancer cells that can be transferred between individuals without the involvement of an infectious agent, such as an oncovirus. [ 1 ] [ 2 ] The evolution of transmissible cancer has occurred naturally in other animal species, but human cancer transmission is rare. [ 2 ]