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Lactobacillus is a genus of gram-positive, aerotolerant anaerobes or microaerophilic, rod-shaped, non-spore-forming bacteria. [2] [3] Until 2020, the genus Lactobacillus comprised over 260 phylogenetically, ecologically, and metabolically diverse species; a taxonomic revision of the genus assigned lactobacilli to 25 genera (see § Taxonomy below).
Lactococcus lactis is a gram-positive bacterium used extensively in the production of buttermilk and cheese, [1] but has also become famous as the first genetically modified organism to be used alive for the treatment of human disease. [2] L. lactis cells are cocci that group in pairs and short chains, and, depending on growth conditions ...
A Lactobacillus acidophilus culture. Lactobacillus acidophilus is an immobile rod-shaped (bacillus), gram-positive organism that ranges in size from 2-10 μm in size. L. acidophilus has one phospholipid bilayer membrane with a large cell wall consisting of peptidoglycan exterior to the membrane.
In 1920, Rettger and Cheplin reported that Metchnikoff's "Bulgarian Bacillus", later called Lactobacillus delbrueckii subsp. bulgaricus, could not live in the human intestine. [70] [non-primary source needed] They conducted experiments involving rats and humans volunteers, feeding them with Lactobacillus acidophilus.
A probiotic organism such as Limosilactobacillus pontis, and other lactobacilli, help by balancing numbers of normal microflora in the human body. [17] Probiotics also give some protection against pathogens , lower levels of cholesterol , cause stimulation of the immune response , and in some cases, protect against specific types of cancer .
Adherence to mucus and human epithelial cells and cell lines and the ability to reduce pathogen adhesion to surfaces is scientifically proven by the research "Influence of Gastrointestinal System Conditions on Adhesion of exopolysaccharide-producing Lactobacillus delbrueckii subsp. bulgaricus strains to Caco-2 Cells" [27]
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