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The setting of reasonable cutoff limits help reduce false positive results that occur from assay limitations. Because of the social and legal consequences, a positive test result must be confirmed by an alternative method, usually Gas Chromatography/Mass spectrometry.
Chromatographic methods specific for amphetamine are employed to prevent false positive results. [253] Chiral separation techniques may be employed to help distinguish the source of the drug, whether prescription amphetamine, prescription amphetamine prodrugs, (e.g., selegiline ), over-the-counter drug products that contain levomethamphetamine ...
New York’s prison system unfairly punished more than 2,000 prisoners after tests of suspected contraband substances falsely tested positive for drugs, according to a report released Thursday.
A drug test (also often toxicology screen or tox screen) is a technical analysis of a biological specimen, for example urine, hair, blood, breath, sweat, or oral fluid/saliva—to determine the presence or absence of specified parent drugs or their metabolites.
Clobenzorex can be detected in urine, which can cause false positives for workplace drug screening. [7] It is one of many drugs that can cause false positives for amphetamine urine drug screening. [8] It may be differentiated from amphetamine use through testing for metabolites such as 4-hydroxyclobenzorex [9] or enantiomeric analysis. [7]
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The FDA recommends for confirmatory testing to be conducted and the placing of a warning label on the presumptive drug test: "This assay provides only a preliminary result. Clinical consideration and professional judgment should be applied to any drug of abuse test result, in evaluating a preliminary positive result.
The false positive rate (FPR) is the proportion of all negatives that still yield positive test outcomes, i.e., the conditional probability of a positive test result given an event that was not present. The false positive rate is equal to the significance level. The specificity of the test is equal to 1 minus the false positive rate.