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Ondansetron, sold under the brand name Zofran among others, is a medication used to prevent nausea and vomiting caused by chemotherapy, radiation therapy, migraines, or surgery. [8] It is also effective for treating gastroenteritis. [9] [10] It can be given orally (by mouth), intramuscularly (injection into a muscle), or intravenously ...
Drug Chemical nature Receptor antagonists T 1/2 (h) Metabolism Dose; Ondansetron: Carbazole derivative 5-HT 3 receptor antagonist and weak 5-HT 4 antagonist 3.9 hours CYP1A1/2, CYP2D6, CYP 3A3/4/5: 150 μg/kg Granisetron: Indazole: 5-HT 3 receptor antagonist 9–11.6 hours CYP3A3/4/5: 10 μg/kg Dolasetron: Indole: 5-HT 3 receptor antagonist 7 ...
Take Zofran. If you know you’re prone to motion sickness and vomiting from motion sickness, your doctor might prescribe ondansetron, also known as Zofran. It comes in a pill and liquid form ...
Aprepitant has also been shown to increase the activity of the 5-HT 3 receptor antagonists ondansetron and the corticosteroid dexamethasone, which are also used to prevent nausea and vomiting caused by chemotherapy. [11] Netupitant has recently been approved by USFDA. It has also been marketed in combination with palonosetron.
Remember that guidelines are not set in stone — rather, they're good rules to follow. For instance, if you’re 30 years old and earn $75,000, you should try to have that much saved in your 401(k).
We're going to get drug costs down at levels that nobody has ever seen before," Trump said. Shares of CVS fell 5.35% to $46.73, Cigna slipped 2.6% to $274.63, while UnitedHealth was down 3.54% at ...
Ondansetron has some utility, with a single dose being associated with less need for intravenous fluids, fewer hospitalizations, and decreased vomiting. [55] [66] [67] [68] Metoclopramide might also be helpful. [68] However, the use of ondansetron might possibly be linked to an increased rate of return to hospital in children. [69]
“This causes a drug interaction called ‘potentiation’ in which, from a drug effects standpoint, 1 plus 1 is greater than 2.” We hope these tips help you stay safe if you choose to drink ...
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