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  2. Levetiracetam - Wikipedia

    en.wikipedia.org/wiki/Levetiracetam

    Levetiracetam, sold under the brand name Keppra among others, is a novel antiepileptic drug [7] used to treat epilepsy. [8] It is used for partial-onset , myoclonic , or tonic–clonic seizures, [ 7 ] and is taken either by mouth as an immediate or extended release formulation or by injection into a vein .

  3. Trough level - Wikipedia

    en.wikipedia.org/wiki/Trough_level

    A trough level is contrasted with a "peak level" (C max), which is the highest level of the medicine in the body, and the "average level", which is the mean level over time. It is widely used in clinical trials for newer medicines to investigate therapeutic effectiveness and safety.

  4. Anticonvulsant - Wikipedia

    en.wikipedia.org/wiki/Anticonvulsant

    The Maternal Outcomes and Neurodevelopmental Effects of Antiepileptic Drugs (MONEAD) study showed that most blood concentrations in breastfed infants of mothers taking carbamazepine, oxcarbazepine, valproate, levetiracetam, and topiramate were quite low, especially in relationship to the mother's level and what the fetal level would have been ...

  5. Therapeutic index - Wikipedia

    en.wikipedia.org/wiki/Therapeutic_index

    The therapeutic window (or pharmaceutical window) of a drug is the range of drug dosages which can treat disease effectively without having toxic effects. [18] Medication with a small therapeutic window must be administered with care and control, frequently measuring blood concentration of the drug, to avoid harm.

  6. Therapeutic drug monitoring - Wikipedia

    en.wikipedia.org/wiki/Therapeutic_drug_monitoring

    Therapeutic drug monitoring (TDM) is a branch of clinical chemistry and clinical pharmacology that specializes in the measurement of medication levels in blood. Its main focus is on drugs with a narrow therapeutic range , i.e. drugs that can easily be under- or overdosed. [ 1 ]

  7. Which cardiovascular drugs may help lower dementia risk? - AOL

    www.aol.com/cardiovascular-drugs-may-help-lower...

    Taking medications like blood pressure and lipid-lowering drugs for more than 5 years is associated with a lower incidence of dementia, a new study has found.

  8. 10 of the Most Expensive Fines in Football - AOL

    www.aol.com/finance/10-most-expensive-fines...

    Fine: $500,000 Bill Belichick, the longtime head coach of the New England Patriots, was fined $500,000 in 2007 for his role in the “Spygate” scandal, one of the most infamous controversies in ...

  9. Reference ranges for blood tests - Wikipedia

    en.wikipedia.org/wiki/Reference_ranges_for_blood...

    This may also be called standard range. In contrast, optimal (health) range or therapeutic target is a reference range or limit that is based on concentrations or levels that are associated with optimal health or minimal risk of related complications and diseases. For most substances presented, the optimal levels are the ones normally found in ...

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