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Aripiprazole, sold under the brand names Abilify and Aristada, among others, is an atypical antipsychotic. [8] It is primarily used in the treatment of schizophrenia , bipolar disorder , and irritability associated with autism spectrum disorder ; [ 8 ] other uses include as an add-on treatment in major depressive disorder and tic disorders . [ 8 ]
A variety of other agents have been tried in bipolar disorder, including benzodiazepines, calcium channel blockers, L-methylfolate, and thyroid hormone. [2] Modafinil (Provigil) and pramipexole (Mirapex) have been suggested for treating cognitive dysfunction associated with bipolar depression, but evidence supporting their use is quite limited.
Depakote (valproic acid/sodium valproate) – an antiepileptic and mood stabilizer used to treat bipolar disorder, neuropathic pain and others; sometimes called an antimanic medication. Depakene is the trade name for the same drug prepared without sodium. Desyrel – an atypical antidepressant used to treat depression and insomnia
Symptoms of Bipolar Disorder. The single most telling symptom of bipolar disorder is the episodic oscillation between high and low mood states — characteristic shifts between depression, normal ...
Aripiprazole (Abilify) – approved as an adjunct to antidepressant for major depression; Brexpiprazole (Rexulti) – approved as an adjunct to antidepressant for major depression; Lumateperone (Caplyta) – approved as an adjunct to mood stabilizer for bipolar depression
Aripiprazole, brexpiprazole, cariprazine, olanzapine, and quetiapine have been approved as adjunct treatment for MDD by the FDA in the United States. [43] [44] Cariprazine, Quetiapine, lurasidone, and lumateperone [45] have been approved, as monotherapies, for bipolar depression, but as of present, lurasidone has not been approved for MDD. [43]
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