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  2. Nephrotoxicity - Wikipedia

    en.wikipedia.org/wiki/Nephrotoxicity

    Nephrotoxicity is toxicity in the kidneys. It is a poisonous effect of some substances, both toxic chemicals and medications, on kidney function. [1] There are various forms, [2] and some drugs may affect kidney function in more than one way. Nephrotoxins are substances displaying nephrotoxicity.

  3. Aminoglycoside - Wikipedia

    en.wikipedia.org/wiki/Aminoglycoside

    Aminoglycoside is a medicinal and bacteriologic category of traditional Gram-negative antibacterial medications that inhibit protein synthesis and contain as a portion of the molecule an amino-modified glycoside . [1] [2] The term can also refer more generally to any organic molecule that contains amino sugar substructures.

  4. Amikacin - Wikipedia

    en.wikipedia.org/wiki/Amikacin

    Around 16% of amikacin crosses the placenta; while the half-life of amikacin in the mother is 2 hours, it is 3.7 hours in the fetus. [14] A pregnant woman taking amikacin with another aminoglycoside has a possibility of causing congenital deafness in her child. While it is known to cross the placenta, amikacin is only partially secreted in ...

  5. Acute tubular necrosis - Wikipedia

    en.wikipedia.org/wiki/Acute_tubular_necrosis

    ATN presents with acute kidney injury (AKI) and is one of the most common causes of AKI. [2] Common causes of ATN include low blood pressure and use of nephrotoxic drugs. [2] The presence of "muddy brown casts" of epithelial cells found in the urine during urinalysis is pathognomonic for ATN. [3] Management relies on aggressive treatment of the ...

  6. Capreomycin - Wikipedia

    en.wikipedia.org/wiki/Capreomycin

    There can be vestibular dysfunction, such as some minor hearing loss after using the medication for 2 to 4 months. A certain block effect of neuromuscular. Can cause allergic reactions: rash, drug fever, facial flushing or pale, asthma, palpitations, sense of suppression in the chest, abdominal pain, anaphylactic shock.

  7. Amphotericin B - Wikipedia

    en.wikipedia.org/wiki/Amphotericin_B

    Other nephrotoxic drugs (such as aminoglycosides): Increased risk of serious renal damage; Cytostatic drugs: Increased risk of kidney damage, hypotension, and bronchospasms; Transfusion of leukocytes: Risk of pulmonal (lung) damage occurs, space the intervals between the application of amphotericin B and the transfusion, and monitor pulmonary ...

  8. Analgesic nephropathy - Wikipedia

    en.wikipedia.org/wiki/Analgesic_nephropathy

    The scarring of the small blood vessels, called capillary sclerosis, is the initial lesion of analgesic nephropathy. [7] Found in the renal pelvis, ureter, and capillaries supplying the nephrons, capillary sclerosis is thought to lead to renal papillary necrosis and, in turn, chronic interstitial nephritis.

  9. Plazomicin - Wikipedia

    en.wikipedia.org/wiki/Plazomicin

    Plazomicin, sold under the brand name Zemdri, is an aminoglycoside antibiotic used to treat complicated urinary tract infections. [2] As of 2019 it is recommended only for those in whom alternatives are not an option. [2] It is given by injection into a vein. [2] Common side effects include kidney problems, diarrhea, nausea, and blood pressure ...