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The intervertebral disc space is typically defined on an X-ray photograph as the space between adjacent vertebrae. In healthy patients, this corresponds to the size of the intervertebral disc. The size of the space can be altered in pathological conditions such as discitis (infection of the intervertebral disc). [medical citation needed]
In the cervical spine, a symptomatic postero-lateral herniation between two vertebrae will impinge on the nerve which exits the spinal canal between those two vertebrae on that side. [21] So, for example, a right postero-lateral herniation of the disc between vertebrae C5 and C6 will impinge on the right C6 spinal nerve.
Spinal stenosis is a narrowing of the canal which can occur in any region of the spine and can be caused by a number of factors. It may result in cervical myelopathy [4] if the narrowed canal impinges on the spinal cord itself. Spinal canal endoscopy can be used to investigate the epidural space, and is an important spinal diagnostic technique ...
The discs between these vertebrae create a natural lumbar lordosis (a spinal curvature that is concave posteriorly). [citation needed] This is due to the difference in thickness between the front and back parts of the intervertebral discs. The lumbar vertebrae are located between the ribcage and the pelvis and are the largest of the vertebrae.
When the space between two adjacent vertebrae narrows, compression of a nerve root emerging from the spinal cord may result in radiculopathy. [1] Radiculopathy is characterized by sensory and motor disturbances, such as severe pain in the neck, shoulder, arm, back, or leg, accompanied by muscle weakness.
Vertebral osteomyelitis often attacks two vertebrae and the corresponding intervertebral disk, causing narrowing of the disc space between the vertebrae. [6] The prognosis for the disease is dependent on where the infection is concentrated in the spine, the time between initial onset and treatment, and what approach is used to treat the disease.
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Between them is the epidural space. The two layers of the dura mater separate at several places, with the meningeal layer projecting deeper into the brain parenchyma forming fibrous septa that compartmentalize the brain tissue. At these sites, the epidural space is wide enough to house the epidural venous sinuses. [2] [4] [5]