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Modafinil, sold under the brand name Provigil among others, is a central nervous system (CNS) stimulant and eugeroic (wakefulness promoter) medication used primarily to treat narcolepsy, [3] [8] [15] a sleep disorder characterized by excessive daytime sleepiness and sudden sleep attacks. [16]
In the United States military, modafinil has been approved for use on certain Air Force missions, and it is being investigated for other uses. [19] As of November 2012, modafinil is the only drug approved by the Air Force as a "go pill" for fatigue management. [20] The use of dextroamphetamine (a.k.a., Dexedrine) is no longer approved. [20] Yes ...
Its best known product has been modafinil, which the firm markets under the brand name Provigil, which has been approved by the Food and Drug Administration for use in treating narcolepsy, shift work sleep disorder, and excessive daytime sleepiness resulting from sleep apnea, though the FDA has held off on approving its use for treating jet lag ...
Thorazine (chlorpromazine) – a phenothiazine antipsychotic used to treat schizophrenia, bipolar mania, and behavioral disorders in children. Notably, the first antipsychotic; Tofranil – a tricyclic antidepressant used to treat depression, anxiety, agitation, panic disorder and bedwetting
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A wakefulness-promoting agent (WPA), or wake-promoting agent, is a drug that increases wakefulness and arousal. [1] [2] [3] They are similar to but distinct from psychostimulants, which not only promote wakefulness but also produce other more overt central nervous system effects, such as improved mood, energy, and motivation.
Armodafinil, sold under the brand name Nuvigil, is a wakefulness-promoting medication which is used to treat excessive daytime sleepiness associated with obstructive sleep apnea, narcolepsy, and shift work disorder. [1] It is also used off-label for certain other indications. [10] The drug is taken by mouth. [1]
Modafinil (Provigil) and pramipexole (Mirapex) have been suggested for treating cognitive dysfunction associated with bipolar depression, but evidence supporting their use is quite limited. [ 25 ] [ 26 ] In addition, riluzole , a glutamatergic drug used in ALS has been studied as an adjunct or monotherapy treatment in bipolar depression, with ...