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Lymphedema can be present at birth, develop at the onset of puberty (praecox), or not become apparent for many years into adulthood (tarda). In men, lower-limb primary lymphedema is most common, occurring in one or both legs. Some cases of lymphedema may be associated with other vascular abnormalities. [4] [citation needed]
The pathophysiology is not yet well understood. Leukocytoclastic vasculitis is proposed to be the underlying cause resulting in reactive lymphedema. [2] Prolonged standing with full knee extension and minimal movement for a prolonged period of time is postulated to induce a temporary failure in pumping the venous and lymphatic systems in the calf region leading to acute gravity-dependent ...
Milroy's disease (MD) is a familial disease characterized by lymphedema, commonly in the legs, caused by congenital abnormalities in the lymphatic system.Disruption of the normal drainage of lymph leads to fluid accumulation and hypertrophy of soft tissues.
Signs and symptoms of CVI in the leg include the following: Varicose veins; Itching ; Hyperpigmentation; Phlebetic lymphedema [7] Chronic swelling of the legs and ankles; Leg ulcer; CVI in the leg may cause the following: Venous stasis; Venous ulcers [8] Stasis dermatitis, [8] also known as varicose eczema
Podoconiosis causes bilateral yet asymmetrical leg swelling with overlying firm nodules. Early on, symptoms may include itching, tingling, widening of the forefoot, and swelling which then progress to soft edema, skin fibrosis, papillomatosis, and nodule formation resembling moss, giving rise to the disease's alternate name of "mossy foot" in some regions of the world. [3]
Awareness of lymphedema -- excessive, debilitating swelling related to lymph node blockage -- is growing, particularly as it affects women after breast cancer treatment. Treatments like surgery ...
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