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The submucosa (or tela submucosa) is a thin layer of tissue in various organs of the gastrointestinal, respiratory, and genitourinary tracts. It is the layer of dense irregular connective tissue that supports the mucosa (mucous membrane) and joins it to the muscular layer, the bulk of overlying smooth muscle (fibers running circularly within layer of longitudinal muscle).
Oral submucous fibrosis (OSF) is a chronic, complex, premalignant (1% transformation risk) condition of the oral cavity, characterized by juxta-epithelial inflammatory reaction and progressive fibrosis of the submucosal tissues (the lamina propria and deeper connective tissues).
The diagnosis is mainly established based on the characteristic symptoms. Stomach pain is the most common sign of a peptic ulcer. [12] More specifically, peptic ulcers erode the muscularis mucosae, at minimum reaching to the level of the submucosa (contrast with erosions, which do not involve the muscularis mucosae). [35]
TNM stage criteria [2] Stage 0 Tis N0 M0 Tis: Tumor confined to mucosa; cancer-in-situ: Stage I T1 N0 M0 T1: Tumor invades submucosa: T2 N0 M0 T2: Tumor invades muscularis propria: Stage II-A T3 N0 M0 T3: Tumor invades subserosa or beyond (without other organs involved) Stage II-B T4a N0 M0 T4a: Tumor perforates the visceral peritoneum: Stage ...
The purpose of the NIDDK diagnostic criteria was to facilitate comparable groups for research. [17] It was not intended to set strict criteria for the diagnosis of IC. Interstitial cystitis may also induce angiogenic factors including VEGF (vascular endothelial growth factor) and PD-ECGF (platelet-derived endothelial cell growth factor ...
The submucosa consists of a dense and irregular layer of connective tissue with blood vessels, lymphatics, and nerves branching into the mucosa and muscular layer. It contains the submucous plexus , and enteric nervous plexus , situated on the inner surface of the muscular layer.
Placental extract injected in the submucosa. [7] Rifampicin 600 mg once daily for 12 weeks. [6] Surgical interventions include: Young's operation. Modified Young's operation. Narrowing of nasal cavities, submucosal injection of Teflon paste (William's operation), section and medial displacement of the lateral wall of the nose.
The submucosa is the tissue that connects the mucosa to the muscle outside the tube. The glands themselves are quite complex. The mucus factory is at the bottom, in the submucosa, it is composed of many little sacs (acini) where the mucus originates. Each sac (acinus) has one end that can open and close (dilate) to allow the mucus out.