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  2. Doxorubicin - Wikipedia

    en.wikipedia.org/wiki/Doxorubicin

    The most dangerous side effect of doxorubicin is dilated cardiomyopathy, leading to congestive heart failure. The rate of cardiomyopathy is dependent on its cumulative dose, with an incidence about 4% when the dose of doxorubicin is 500–550 mg/m 2, 18% when the dose is 551–600 mg/m 2 and 36% when the dose exceeds 600 mg/m 2. [19]

  3. Amyloid cardiomyopathy - Wikipedia

    en.wikipedia.org/wiki/Amyloid_cardiomyopathy

    Chemotherapy can treat amyloidosis if it is related to immunoglobulins. [4] Liver transplant can treat amyloidosis if it is related to familial transthyretin. [4]Acoramidis (Attruby) was approved for medical use in the United States in November 2024, to treat adults with cardiomyopathy of wild-type or variant (hereditary) transthyretin-mediated amyloidosis (ATTR-CM) to reduce death and ...

  4. Anthracycline - Wikipedia

    en.wikipedia.org/wiki/Anthracycline

    As an example, the incidence of congestive heart failure is 4.7%, 26% and 48% respectively when patients received doxorubicin at 400 mg/m 2, 550 mg/m 2 and 700 mg/m 2. [4] Therefore, the lifetime cumulative doxorubicin exposure is limited to 400–450 mg/m 2 in order to reduce congestive heart failure incidence to less than 5%, although ...

  5. List of antineoplastic agents - Wikipedia

    en.wikipedia.org/wiki/List_of_antineoplastic_agents

    Cardiovascular complications, such as ischaemic heart disease, venous thromboembolism, congestive heart failure, pulmonary embolism, myocardial infarction and cerebrovascular failure. Ixabepilone: IV: Promotes tubulin polymerisation and stabilises microtubular function, causing cell cycle arrest at G2/M phase and subsequently induces apoptosis

  6. Heart failure - Wikipedia

    en.wikipedia.org/wiki/Heart_failure

    Heart failure (HF), also known as congestive heart failure (CHF), is a syndrome caused by an impairment in the heart's ability to fill with and pump blood.. Although symptoms vary based on which side of the heart is affected, HF typically presents with shortness of breath, excessive fatigue, and bilateral leg swelling. [3]

  7. Epirubicin - Wikipedia

    en.wikipedia.org/wiki/Epirubicin

    It was first observed in adult cancer patients as clinical congestive heart failure (CHF), characterized by pulmonary oedema, fluid overload, and effort intolerance, was initially reported in 1979 by Von Hoff et al. [14] at 2.2% overall with a cumulative doxorubicin dose-dependent incidence of CHF of 3%, 7%, and 18% at 400, 550, and 700 mg/m2 ...

  8. New Hair Loss Treatment May Impact Heart Health ... - AOL

    www.aol.com/lifestyle/hair-loss-treatment-may...

    People may experience hair loss for various reasons—perimenopause, chemotherapy, alopecia and more. It’s also normal to find hair in the shower ; that doesn’t mean you have a medical condition.

  9. Trastuzumab - Wikipedia

    en.wikipedia.org/wiki/Trastuzumab

    In 2–7% of cases, [52] trastuzumab is associated with cardiac dysfunction, which includes congestive heart failure. As a result, regular cardiac screening with either a MUGA scan or echocardiography is commonly undertaken during the trastuzumab treatment period.

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