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  2. C-terminal telopeptide - Wikipedia

    en.wikipedia.org/wiki/C-terminal_telopeptide

    The C-terminal telopeptide (CTX), also known as carboxy-terminal collagen crosslinks, is the C-terminal telopeptide of fibrillar collagens such as collagen type I and type II. It is used as a biomarker in the serum to measure the rate of bone turnover .

  3. Cross-link - Wikipedia

    en.wikipedia.org/wiki/Cross-link

    Compromised collagen in the cornea, a condition known as keratoconus, can be treated with clinical crosslinking. [14] In biological context crosslinking could play a role in atherosclerosis through advanced glycation end-products (AGEs), which have been implicated to induce crosslinking of collagen, which may lead to vascular stiffening.

  4. Collagen - Wikipedia

    en.wikipedia.org/wiki/Collagen

    Collagen's insolubility was a barrier to the study of monomeric collagen until it was found that tropocollagen from young animals can be extracted because it is not yet fully crosslinked. However, advances in microscopy techniques (i.e. electron microscopy (EM) and atomic force microscopy (AFM)) and X-ray diffraction have enabled researchers to ...

  5. Corneal cross-linking - Wikipedia

    en.wikipedia.org/wiki/Corneal_cross-linking

    Corneal cross-linking (CXL) with riboflavin (vitamin B 2) and UV-A light is a surgical treatment for corneal ectasia such as keratoconus, PMD, and post-LASIK ectasia. It is used in an attempt to make the cornea stronger. According to a 2015 Cochrane review, there is insufficient evidence to determine if it is useful in keratoconus. [2]

  6. N-terminal telopeptide - Wikipedia

    en.wikipedia.org/wiki/N-terminal_telopeptide

    The N-terminal telopeptide (NTX), also known as amino-terminal collagen crosslinks, is the N-terminal telopeptide of fibrillar collagens such as collagen type I and type II. It is used as a biomarker to measure the rate of bone turnover. NTX can be measured in the urine (uNTX) or serum (serum NTX). [1]

  7. Glucosepane - Wikipedia

    en.wikipedia.org/wiki/Glucosepane

    Glucosepane is a lysine-arginine protein cross-linking product and advanced glycation end product (AGE) derived from D-glucose. [1] It is an irreversible, covalent cross-link product that has been found to make intermolecular and intramolecular cross-links in the collagen of the extracellular matrix (ECM) and crystallin of the eyes. [2]

  8. Cross-linking - Wikipedia

    en.wikipedia.org/wiki/Cross-linking

    Cross-linking may refer to Cross-link , a chemical bond of one polymer chain to another Corneal collagen cross-linking , a parasurgical treatment for corneal ectasia and keratoconus

  9. Lysyl oxidase - Wikipedia

    en.wikipedia.org/wiki/Lysyl_oxidase

    LOX secreted by hypoxic breast tumor cells crosslinks collagen in the basement membrane and is essential for CD11b+ myeloid cell recruitment. CD11b+ cells in turn adhere to crosslinked collagen and produce matrix metalloproteinase-2, which cleaves collagen, enhancing the invasion of metastasizing tumor cells. In contrast, LOX inhibition ...

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