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If symptoms of discontinuation are severe, or do not respond to symptom management, the antidepressant can be reinstated and then withdrawn more cautiously, or by switching to a drug with a longer half life (e.g., fluoxetine), and then tapering and discontinuing that drug. [21]
The first time Horowitz tried to wean off of Lexapro, forums helped connect him to “thousands of people who had the exact same experience as me. They had the extreme symptoms that I did—I ...
Treatment for withdrawal usually involves weaning over a 3- to 21-day period if the infusion lasted for more than a week. [134] Symptoms include tremors, agitation, sleeplessness, inconsolable crying, diarrhea and sweating. In total, over fifty withdrawal symptoms are listed in this review article.
This technique may be used if your medication puts you at risk for withdrawal symptoms, which may occur when some antidepressants are stopped without a gradual taper. Taper and moderate switch.
Symptoms are most likely to occur when you stop taking an antidepressant cold turkey (which, by the way, isn’t advised)—or in cases where you’re in the process of tapering off.
More severe cases are often successfully treated by temporary reintroduction of the drug with a slower tapering-off rate. [88] Sertraline and SSRI antidepressants in general may be associated with bruxism and other movement disorders. [89] [90] Sertraline appears to be associated with microscopic colitis, a rare condition of unknown etiology. [91]
The rebound effect, or rebound phenomenon, is the emergence or re-emergence of symptoms that were either absent or controlled while taking a medication, but appear when that same medication is discontinued, or reduced in dosage. In the case of re-emergence, the severity of the symptoms is often worse than pretreatment levels.
Sertraline (Zoloft) As an SSRI antidepressant, escitalopram is commonly prescribed to treat depression. The FDA also approves it for the treatment of generalized anxiety disorder (GAD).