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A cell during anaphase. Microtubules are visible in green. Stages of late M phase in a vertebrate cell. Anaphase (from Ancient Greek ἀνα-() 'back, backward' and φάσις (phásis) 'appearance') is the stage of mitosis after the process of metaphase, when replicated chromosomes are split and the newly-copied chromosomes (daughter chromatids) are moved to opposite poles of the cell.
As chromosomes have two kinetochores associated back-to-back (one on each sister chromatid), when one of them becomes attached to the microtubules generated by one of the cellular poles, the kinetochore on the sister chromatid becomes exposed to the opposed pole; for this reason, most of the times the second kinetochore becomes attached to the ...
Micrograph showing condensed chromosomes in blue, kinetochores in pink, and microtubules in green during metaphase of mitosis. In cell biology, the spindle apparatus is the cytoskeletal structure of eukaryotic cells that forms during cell division to separate sister chromatids between daughter cells.
Biorientation is the phenomenon whereby microtubules emanating from different microtubule organizing centres (MTOCs) attach to kinetochores of sister chromatids.This results in the sister chromatids moving to opposite poles of the cell during cell division, and thus results in both daughter cells having the same genetic information.
Using different types of genetic studies, it has been established that diverse kinds of defects are able to activate the SAC: spindle depolymerization, [8] [9] the presence of dicentric chromosomes (with two centromeres), [10] centromeres segregating in an aberrant way, [11] defects in the spindle pole bodies in S. cerevisiae, [12] defects in ...
Chromosome segregation is the process in eukaryotes by which two sister chromatids formed as a consequence of DNA replication, or paired homologous chromosomes, separate from each other and migrate to opposite poles of the nucleus. This segregation process occurs during both mitosis and meiosis. Chromosome segregation also occurs in prokaryotes ...
During metaphase, the kinetochore microtubules extending from each centrosome connect to the centromeres of the chromosomes. Next, during anaphase, the kinetochore microtubules pull the sister chromatids apart into individual chromosomes and pull them towards the centrosomes, located at opposite ends of the cell. This allows the cell to divide ...
This is an accepted version of this page This is the latest accepted revision, reviewed on 19 December 2024. Process in which chromosomes are replicated and separated into two new identical nuclei For the type of cell division in sexually reproducing organisms used to produce gametes, see Meiosis. For excessive constriction of the pupils, see Miosis. For the parasitic infestation, see Myiasis ...