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Calcium pyrophosphate dihydrate (CPPD) crystal deposition disease, also known as pseudogout and pyrophosphate arthropathy, is a rheumatologic disease which is thought to be secondary to abnormal accumulation of calcium pyrophosphate dihydrate crystals within joint soft tissues. [1] The knee joint is most commonly affected. [2]
For example, mechanical obstruction by mineral stones causes nephrolithiasis, urolithiasis, cholecystolithiasis, choledocholithiasis, docholithiasis, and sialolithiasis, and acute inflammation caused by crystals in joints causes gout and pseudogout. [1] Renal diseases are also common in crystallopathies, including: [1]
A magnesium deficiency may cause chondrocalcinosis, and there is anecdotal evidence that magnesium supplementation may reduce or alleviate symptoms. [7] In some cases, arthritis from injury can cause chondrocalcinosis. [8] Other causes of chondrocalcinosis include: [4] Hypercalcaemia, especially when caused by hyperparathyroidism; Arthritis ...
Gout can also appear similar to another condition called calcium pyrophosphate deposition (CPPD) — or pseudogout. However, CPPD happens due to the formation of calcium phosphate crystals, not ...
Gout (/ ɡ aʊ t / GOWT [7]) is a form of inflammatory arthritis characterized by recurrent attacks of pain in a red, tender, hot, and swollen joint, [2] [8] caused by the deposition of needle-like crystals of uric acid known as monosodium urate crystals. [9]
Deposition of dihydrate crystals in cartilage are responsible for the severe joint pain in cases of calcium pyrophosphate deposition disease (pseudo gout) whose symptoms are similar to those of gout. [1] Ca 2 P 2 O 7 is commonly used as a mild abrasive agent in toothpastes because of its insolubility and nonreactivity toward fluoride. [2]
Crystal arthropathy is a class of joint disorder (called arthropathy) that is characterized by accumulation of tiny crystals in one or more joints. Polarizing microscopy and application of other crystallographic techniques have improved identification of different microcrystals including monosodium urate , calcium pyrophosphate dihydrate ...
Pseudogout (also referred to as calcium pyrophosphate dihydrate crystal deposition disease) is another type of crystalline arthritis that presents very similarly to gout but is caused by the deposition of rhomboid-shaped calcium pyrophosphate dihydrate (CPPD) crystals. The knees, wrists, and fingers are the most common joints affected by ...
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