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Many gases have toxic properties, which are often assessed using the LC 50 (median lethal concentration) measure. In the United States, many of these gases have been assigned an NFPA 704 health rating of 4 (may be fatal) or 3 (may cause serious or permanent injury), and/or exposure limits (TLV, TWA/PEL, STEL, or REL) determined by the ACGIH professional association.
The exposure to bromine immediately dangerous to life and health (IDLH) is 3 ppm. [84] Bromine is classified as an extremely hazardous substance in the United States as defined in Section 302 of the U.S. Emergency Planning and Community Right-to-Know Act (42 U.S.C. 11002), and is subject to strict reporting requirements by facilities which ...
PBDEs have been found in people all over the world. [ 8 ] Some brominated flame retardants were identified as persistent, bioaccumulative, and toxic to both humans and the environment and were suspected of causing neurobehavioral effects and endocrine disruption .
A study in the journal Chemosphere in December concluded that toxic brominated flame retardants and organophosphate flame retardants might be present at dangerous levels in some products ...
The FDA said it banned brominated vegetable oil after "the results of studies conducted in collaboration with the National Institutes of Health (NIH) found the potential for adverse health effects ...
Bromism is the syndrome which results from the long-term consumption of bromine, usually through bromine-based sedatives such as potassium bromide and lithium bromide. Bromism was once a very common disorder, being responsible for 5 to 10% of psychiatric hospital admissions, but is now uncommon since bromide was withdrawn from clinical use in ...
The same features causing persistence of dioxins in the environment also cause very slow elimination in humans and animals. Because of low water solubility, kidneys cannot excrete them in urine as such. They must first be metabolised to more-water-soluble metabolites, but that metabolism, especially in humans, is extremely slow.
Immediately Dangerous To Life or Health Concentration by NIOSH: "The revised IDLH for methyl bromide is 250 ppm based on acute inhalation toxicity data in humans [Clarke et al. 1945]. This may be a conservative value due to the lack of relevant acute toxicity data for workers exposed to concentrations above 220 ppm.