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Pituitary pars intermedia dysfunction (PPID), or equine Cushing's disease, is an endocrine disease affecting the pituitary gland of horses. It is most commonly seen in older animals, [ 1 ] and is classically associated with the formation of a long, wavy coat ( hirsutism ) and chronic laminitis .
Cyproheptadine, sold under the brand name Periactin among others, is a first-generation antihistamine with additional anticholinergic, antiserotonergic, and local anesthetic properties. It was patented in 1959 and came into medical use in 1961. [ 5 ]
If Cushing's is suspected it can be confirmed via urinalysis of the creatine/cortisol ratio. L-thyroxine is the most common method of treating hypothyroidism in dogs, if used to treat a dog with Cushing's the dog will likely display polyuria and polydipsia and the condition may worsen. [13]
Equine metabolic syndrome (EMS) is an endocrinopathy affecting horses and ponies. It is of primary concern due to its link to obesity, insulin dysregulation , and subsequent laminitis .
1. Ketogenic Diet. Cancer cells rely on glucose for energy to grow. The ketogenic diet is a way to provide an alternative energy source to normal cells in the dog's body while starving the cancer ...
Pituitary pars intermedia dysfunction, or Cushing's disease, is common in older horses and ponies and causes an increased predisposition to laminitis. Equine metabolic syndrome is a subject of much new research and is increasingly believed to have a major role in laminitis. It involves many factors such as cortisol metabolism and insulin ...
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