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  2. Diseases and epidemics of the 19th century - Wikipedia

    en.wikipedia.org/wiki/Diseases_and_epidemics_of...

    The disease killed an estimated 400,000 Europeans annually during the 19th century and one-third of all the blindness of that time was caused by smallpox. 20 to 60% of all the people that were infected died and 80% of all the children with the infection also died. It caused also many deaths in the 20th century, over 300–500 million.

  3. Smallpox - Wikipedia

    en.wikipedia.org/wiki/Smallpox

    Smallpox was an infectious disease caused by variola virus (often called smallpox virus), which belongs to the genus Orthopoxvirus. [7] [11] The last naturally occurring case was diagnosed in October 1977, and the World Health Organization (WHO) certified the global eradication of the disease in 1980, [10] making smallpox the only human disease to have been eradicated to date.

  4. History of smallpox - Wikipedia

    en.wikipedia.org/wiki/History_of_smallpox

    During the 18th century the disease killed an estimated 400,000 Europeans each year, including five reigning monarchs, and was responsible for a third of all blindness. [4] Between 20 and 60% of all those infected—and over 80% of infected children—died from the disease.

  5. 1837 Great Plains smallpox epidemic - Wikipedia

    en.wikipedia.org/wiki/1837_Great_Plains_smallpox...

    [24] So great was the distrust of the settlers that the Mandan chief Four Bears denounced the white man, whom he had previously treated as brothers, for bringing the disease to his people. After losing his wife and children to smallpox, and acquiring the affliction himself, he gave his final speech to the Arikara and Mandan tribes imploring ...

  6. 1775–1782 North American smallpox epidemic - Wikipedia

    en.wikipedia.org/wiki/1775–1782_North_American...

    Smallpox was a dangerous disease caused by the variola major virus. The most common type of smallpox, ordinary, historically has devastated populations with a 30% death rate. The smallpox virus is transmittable through bodily fluids and materials contaminated with infected materials.

  7. Antonine Plague - Wikipedia

    en.wikipedia.org/wiki/Antonine_Plague

    The Antonine plague spread throughout the Roman Empire and infected many millions of people. The pandemic erupted during the last years of what is often considered the "golden age" [17] of Rome during the reign of co-emperor Marcus Aurelius. The Roman Empire at that time had a population estimated at 75 million people.

  8. List of epidemics and pandemics - Wikipedia

    en.wikipedia.org/wiki/List_of_epidemics_and...

    There have been various major infectious diseases with high prevalence worldwide, but they are currently not listed in the above table as epidemics/pandemics due to the lack of definite data, such as time span and death toll. An Ethiopian child with malaria, a disease with an annual death rate of 619,000 as of 2021. [18]

  9. 1992–1993 Jack in the Box E. coli outbreak - Wikipedia

    en.wikipedia.org/wiki/1992–1993_Jack_in_the_Box...

    A total of 171 people required hospitalization. [22] The majority of those who presented symptoms and were clinically diagnosed (but not hospitalized) were children under 10 years old. [6] [7] Of the infected children, 45 required hospitalization – 38 had serious kidney problems and 21 required dialysis. [23] Four children died:

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