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  2. Complementarity (molecular biology) - Wikipedia

    en.wikipedia.org/wiki/Complementarity_(molecular...

    Purines are larger than pyrimidines. Both types of molecules complement each other and can only base pair with the opposing type of nucleobase. In nucleic acid, nucleobases are held together by hydrogen bonding, which only works efficiently between adenine and thymine and between guanine and cytosine. The base complement A = T shares two ...

  3. Complement system - Wikipedia

    en.wikipedia.org/wiki/Complement_system

    Scheme of the complement system. The complement system, also known as complement cascade, is a part of the humoral, innate immune system and enhances (complements) the ability of antibodies and phagocytic cells to clear microbes and damaged cells from an organism, promote inflammation, and attack the pathogen's cell membrane. [1]

  4. Complement control protein - Wikipedia

    en.wikipedia.org/wiki/Complement_control_protein

    Complement control proteins are proteins that interact with components of the complement system. The complement system is tightly regulated by a network of proteins known as "regulators of complement activation (RCA)" that help distinguish target cells as "self" or "non-self."

  5. Factor D - Wikipedia

    en.wikipedia.org/wiki/Factor_D

    The encoded protein is a component of the alternative complement pathway best known for its role in humoral suppression of infectious agents. Finally, the encoded protein has a high level of expression in fat, suggesting a role for adipose tissue in immune system biology. [3] Alternative pathway. ( 4. Is factor D cleaving B to Bb and Ba)

  6. Complementation (genetics) - Wikipedia

    en.wikipedia.org/wiki/Complementation_(genetics)

    These rules (patterns) are not without exceptions. Non-allelic mutants may occasionally fail to complement (this is known as "non-allelic non-complementation" or "unlinked non-complementation"). This is an uncommon occurrence that depends on the type of mutants being investigated. Two mutations, for example, could be synthetically dominant ...

  7. Biological rules - Wikipedia

    en.wikipedia.org/wiki/Biological_rules

    Foster's rule, the island rule, or the island effect states that members of a species get smaller or bigger depending on the resources available in the environment. [ 28 ] [ 29 ] [ 30 ] The rule was first stated by J. Bristol Foster in 1964 in the journal Nature , in an article titled "The evolution of mammals on islands".

  8. Alternative complement pathway - Wikipedia

    en.wikipedia.org/wiki/Alternative_complement_pathway

    The classical and alternative complement pathways. Alternative pathway. (Some labels are in Polish.) The alternative pathway is a type of cascade reaction of the complement system and is a component of the innate immune system, a natural defense against infections.

  9. Complement-dependent cytotoxicity - Wikipedia

    en.wikipedia.org/wiki/Complement-dependent_cyto...

    Complement-dependent cytotoxicity (CDC) is an effector function of IgG and IgM antibodies.When they are bound to surface antigen on target cell (e.g. bacterial or viral infected cell), the classical complement pathway is triggered by bonding protein C1q to these antibodies, resulting in formation of a membrane attack complex (MAC) and target cell lysis.