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The polyol pathway is a two-step process that converts glucose to fructose. [1] In this pathway glucose is reduced to sorbitol, which is subsequently oxidized to fructose. It is also called the sorbitol-aldose reductase pathway. The pathway is implicated in diabetic complications, especially in microvascular damage to the retina, [2] kidney, [3 ...
Advanced glycation end products (AGEs) are proteins or lipids that become glycated as a result of exposure to sugars. [1] They are a bio-marker implicated in aging and the development, or worsening, of many degenerative diseases, such as diabetes, atherosclerosis, chronic kidney disease, and Alzheimer's disease. [2]
In blood-glucose levels, insulin lowers the concentration of glucose in the blood. The lower blood-glucose level (a product of the insulin secretion) triggers glucagon to be secreted, and repeats the cycle. [23] In order for blood glucose to be kept stable, modifications to insulin, glucagon, epinephrine and cortisol are made.
Dr. Hennis says, "If you have very high blood glucose levels and also experience frequent urination and keep drinking liquids even when you aren't thirsty, you should go get checked as soon as you ...
Renal glucose reabsorption is the part of kidney (renal) physiology that deals with the retrieval of filtered glucose, preventing it from disappearing from the body through the urine. If glucose is not reabsorbed by the kidney, it appears in the urine, in a condition known as glycosuria. This is associated with diabetes mellitus. [1]
Hyperglycemia or hyperglycaemia is a condition where unusually high amount of glucose is present in blood. It is defined as blood glucose level exceeding 6.9 mmol/L (125 mg/dL) after fasting for 8 hours and 10 mmol/L (180 mg/dL) 2 hours after eating. [1] [2]
Dark tea may mimic the effects of a class of a relatively new class of diabetes drugs called SGLT-2 inhibitors, which allow the kidneys to excrete more glucose, thus lowering blood sugar levels ...
The presence of glucose in the urine is known as glycosuria. In people with normal blood sugar levels, the amount of glucose in the urine should be negligible as it is reabsorbed by the renal tubules. [72] High blood sugar levels (hyperglycemia) cause excess glucose to
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