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  2. RNA world - Wikipedia

    en.wikipedia.org/wiki/RNA_world

    The RNA world hypothesis places RNA at center-stage when life originated. The RNA world hypothesis is supported by the observations that ribosomes are ribozymes: [120] [121] the catalytic site is composed of RNA, and proteins hold no major structural role and are of peripheral functional importance. This was confirmed with the deciphering of ...

  3. Leslie Orgel - Wikipedia

    en.wikipedia.org/wiki/Leslie_Orgel

    In the late 1960s, Orgel proposed that life was based on RNA before it was based on DNA or proteins. His theory included genes based on RNA and RNA enzymes. [17] This view would be developed and shaped into the now widely accepted RNA world hypothesis. Almost thirty years later, Orgel wrote a lengthy review of the RNA World hypothesis. [18]

  4. RNP world - Wikipedia

    en.wikipedia.org/wiki/RNP_world

    This difference between protein and ribonucleoprotein catalysts can be explained by extending the RNA world theory. The older RNA molecules were originally self-catalyzed through ribozymes, which evolved the assistance of proteins to form RNP. Thereafter, the newer DNA molecule used only the more efficient protein processes from the start. Thus ...

  5. Polyelectrolyte theory of the gene - Wikipedia

    en.wikipedia.org/wiki/Polyelectrolyte_theory_of...

    Although RNA is often described as a genetic biopolymer because of its theorized role as life’s first unit of inheritance (RNA World), it is not entirely COSMIC-LOPER. RNA, especially sequences high in guanine (G), is capable of folding and performing enzyme-type chemistry. [2] [18] Folding in guanine-rich RNA sequences prevents the ...

  6. The Major Transitions in Evolution - Wikipedia

    en.wikipedia.org/wiki/The_Major_Transitions_in...

    Transitions described in the book Transition from: Transition to: Notes Replicating molecules "Populations" of molecules in compartments Can't observe [clarification needed] Independent replicators (probably RNA) Chromosomes: RNA world hypothesis: RNA as both genes and enzymes: DNA as genes; proteins as enzymes Prokaryotes: Eukaryotes

  7. Ribozyme - Wikipedia

    en.wikipedia.org/wiki/Ribozyme

    RNA can also act as a hereditary molecule, which encouraged Walter Gilbert to propose that in the distant past, the cell used RNA as both the genetic material and the structural and catalytic molecule rather than dividing these functions between DNA and protein as they are today; this hypothesis is known as the "RNA world hypothesis" of the ...

  8. Today's Wordle Hint, Answer for #1264 on Wednesday, December ...

    www.aol.com/todays-wordle-hint-answer-1264...

    The best books of 2024, according to Goodreads. See all deals. In Other News. Entertainment. Entertainment. People. Ryan Reynolds has been Blake Lively's 'rock' during 'It Ends with Us' ordeal: A ...

  9. First universal common ancestor - Wikipedia

    en.wikipedia.org/wiki/First_universal_common...

    In the eocyte hypothesis, the organism at the root of all eocytes may have been a ribocyte of the RNA-world. For cellular DNA and DNA handling, an "out of virus" scenario has been proposed: storing genetic information in DNA may have been an innovation performed by viruses and later handed over to ribocytes twice, once transforming them into bacteria and once transforming them into archaea.