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A newly identified colon cancer gene may drive the disease by making the environment in the vicinity of tumors more hospitable to them, researchers say. Why does colon cancer grow so fast? Study ...
Cancer cells, however, have the ability to grow without these external signals. There are multiple ways in which cancer cells can do this: by producing these signals themselves, known as autocrine signaling ; by permanently activating the signaling pathways that respond to these signals; or by destroying 'off switches' that prevents excessive ...
In cancer cells, major changes in gene expression increase glucose uptake to support their rapid growth. Unlike normal cells, which produce lactate only when oxygen is low, cancer cells convert much of the glucose to lactate even in the presence of adequate oxygen. This is known as the “Warburg Effect.”
Although there are over 50 identifiable hereditary forms of cancer, less than 0.3% of the population are carriers of a cancer-related genetic mutation and these make up less than 3–10% of all cancer cases. [3] The vast majority of cancers are non-hereditary ("sporadic cancers"). Hereditary cancers are primarily caused by an inherited genetic ...
A: In 2024, precision cancer treatment made big strides with many new drug approvals by the FDA, specifically for treatments guided by specific biomarkers, which means treatments can be more ...
Cancer cells have unique features that make them "immortal" according to some researchers. The enzyme telomerase is used to extend the cancer cell's life span. While the telomeres of most cells shorten after each division, eventually causing the cell to die, telomerase extends the cell's telomeres. This is a major reason that cancer cells can ...
The researchers found that the bladder cancer cells grew at a “much faster” rate in mice that had fewer Y chromosomes compared to those with many, according to the release.
This condition also includes the inactivation of specific tumor suppressor genes (see below). If the condition is not fulfilled, the cell may cease to grow and can proceed to die. This makes identification of the stage and type of cancer cell that grows under the control of a given oncogene crucial for the development of treatment strategies.