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In cancer cells, major changes in gene expression increase glucose uptake to support their rapid growth. Unlike normal cells, which produce lactate only when oxygen is low, cancer cells convert much of the glucose to lactate even in the presence of adequate oxygen. This is known as the “Warburg Effect.”
A newly identified colon cancer gene may drive the disease by making the environment in the vicinity of tumors more hospitable to them, researchers say. Why does colon cancer grow so fast? Study ...
This condition also includes the inactivation of specific tumor suppressor genes (see below). If the condition is not fulfilled, the cell may cease to grow and can proceed to die. This makes identification of the stage and type of cancer cell that grows under the control of a given oncogene crucial for the development of treatment strategies.
Cancer treatment drugs pose a strong selective force on all types of cells in tumors, including cancer stem cells, which would be forced to evolve resistance to the treatment. Cancer stem cells do not always have to have the highest resistance among the cells in the tumor to survive chemotherapy and re-emerge afterwards.
Scientists suggest the findings could one day allow doctors to use a blood test to predict how a patient’s cancer may progress. Genetic clues reveal how cancer might grow and spread – study ...
The findings raise hope for more effective treatments for pancreatic cancer, which has a poor survival rate. Shutdown of crucial gene helps world’s deadliest cancer grow rapidly – study Skip ...
Cancer cells, however, have the ability to grow without these external signals. There are multiple ways in which cancer cells can do this: by producing these signals themselves, known as autocrine signaling ; by permanently activating the signaling pathways that respond to these signals; or by destroying 'off switches' that prevents excessive ...
Breast cancer was the only type for which treatment advances prevented more deaths. Quitting smoking was found to be the most beneficial prevention strategy overall, credited for averting 3.45 ...
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