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Pancytopenia is a medical condition in which there is significant reduction in the number of almost all blood cells (red blood cells, white blood cells, platelets, monocytes, lymphocytes, etc.). If only two parameters from the complete blood count are low, the term bicytopenia can be used. The diagnostic approach is the same as for pancytopenia.
This is a shortened version of the fourth chapter of the ICD-9: Diseases of the Blood and Blood-forming Organs. It covers ICD codes 280 to 289. The full chapter can be found on pages 167 to 175 of Volume 1, which contains all (sub)categories of the ICD-9. Volume 2 is an alphabetical index of Volume 1.
With Parvovirus infection, bone marrow recovery typically occurs within 10 days and erythropoiesis resumes. [8] Parvovirus IgG/IgM may be obtained to assess for active infection. Patients may require IVIG or replacement of blood products during this transient bone marrow failure to reduce the chance of serious complications from the severe anemia.
Relapses are common. Relapse following ATG/ciclosporin use can sometimes be treated with a repeated course of therapy. In addition, 10–15% of severe aplastic anemia cases evolve into myelodysplastic syndrome and leukemia. [40] According to one study, 15.9% of children who responded to immunosuppressive therapy eventually relapsed. [41]
This is a shortened version of the first chapter of the ICD-9: Infectious and Parasitic Diseases. It covers ICD codes 001 to 139 . The full chapter can be found on pages 49 to 99 of Volume 1, which contains all (sub)categories of the ICD-9.
Many individuals are asymptomatic, and blood cytopenia or other problems are identified as a part of a routine blood count: [10] Neutropenia, anemia, and thrombocytopenia; Splenomegaly or rarely hepatomegaly; Abnormal granules in cells, abnormal nuclear shape and size
Laboratory findings include pancytopenia, marrow aplasia, abnormal liver enzymes, and electrolyte imbalance (when diarrhea is present). [citation needed] TA-GvHD can be suspected from a biopsy of the affected skin or liver, [4] and established by HLA analysis of the circulating lymphocytes. This testing can identify circulating lymphocytes with ...
Diamond–Blackfan anemia (DBA) is a congenital erythroid aplasia that usually presents in infancy. [3] DBA causes low red blood cell counts (), without substantially affecting the other blood components (the platelets and the white blood cells), which are usually normal.