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A muscle relaxant is a drug that affects skeletal muscle function and decreases the muscle tone. It may be used to alleviate symptoms such as muscle spasms , pain , and hyperreflexia . The term "muscle relaxant" is used to refer to two major therapeutic groups: neuromuscular blockers and spasmolytics .
Tizanidine, sold under the brand name Zanaflex among others, is an alpha-2 (α 2) adrenergic receptor agonist, [2] similar to clonidine, that is used to treat muscle spasticity due to spinal cord injury, multiple sclerosis, and spastic cerebral palsy. [3] Effectiveness appears similar to baclofen or diazepam. [4] It is taken by mouth. [5]
Benzodiazepines are well known for their strong muscle-relaxing properties and can be useful in the treatment of muscle spasms, [24]: 577–578 although tolerance often develops to their muscle relaxant effects. [15] Baclofen [65] or tizanidine are sometimes used as an alternative to benzodiazepines. Tizanidine has been found to have superior ...
It is better to use an effective, well-known analgesic for patients complaining of muscle pain, starting with paracetamol. [16] Although muscle relaxants may have the major side effect of sedation, thiocolchicoside is free from sedation effects, likely due to its lack of potentiation of GABA A receptors. [7]
Eurodin, Prosom – a benzodiazepine derivative with anxiolytic, anticonvulsant, hypnotic, sedative and skeletal muscle relaxant properties, commonly prescribed for short-term treatment of insomnia F [ edit ]
Long-term use of muscle relaxants in such cases is poorly supported. [8] Spasm may also be seen in movement disorders featuring spasticity in neurologic conditions such as cerebral palsy, multiple sclerosis, and spinal cord disease. Medications are commonly used for spastic movement disorders, but research has not shown functional benefit for ...
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It can be given orally (by mouth), by intramuscular injection (injection into a muscle), or intravenously (injection into a vein). [6] Chlorpromazine is in the typical antipsychotic class, [6] and, chemically, is one of the phenothiazines. Its mechanism of action is not entirely clear but is believed to be related to its ability as a dopamine ...
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