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  2. Lokivetmab - Wikipedia

    en.wikipedia.org/wiki/Lokivetmab

    Lokivetmab, trade name Cytopoint, is a monoclonal antibody used to treat atopic dermatitis in dogs. [1] It acts against interleukin 31 (IL-31), [2] which is a cytokine involved in causing itchiness (pruritus). [2] Lokivetmab is administered by subcutaneous injection; each dose is effective for four to eight weeks. [3]

  3. List of therapeutic monoclonal antibodies - Wikipedia

    en.wikipedia.org/wiki/List_of_therapeutic...

    Brolucizumab [25] Beovu: scFv: humanized: vascular endothelial growth factor A (VEGFA) Y: wet age-related macular degeneration Brontictuzumab [6] mab: humanized: Notch 1: cancer Burosumab [18] Crysvita: mab: human: FGF 23: Y: X-linked hypophosphatemia: Cabiralizumab [41] mab: humanized: CSF1R: metastatic pancreatic cancer Camidanlumab tesirine ...

  4. Immunosuppressive drug - Wikipedia

    en.wikipedia.org/wiki/Immunosuppressive_drug

    They act by inhibiting gene expression of cytokines including Interleukin 1 (IL-1), IL-2, IL-3, IL-4, IL-5, IL-6, IL-8, and TNF-alpha by binding to corticosteroid response elements on DNA. [1] This decrease in cytokine production reduces T cell proliferation. With decreased T cell proliferation there is decreased production of IL-2.

  5. America’s Most Admired Lawbreaker - The Huffington Post

    highline.huffingtonpost.com/.../chapter-1.html

    By Steven Brill Letter From the Editors Backstage at Johnson & Johnson. On May 20, about 100 stock analysts gathered in the ballroom of the Hyatt Regency Hotel in New Brunswick, New Jersey, to hear good news from top executives at Johnson & Johnson: The company had 10 new drugs in the pipeline that might achieve more than a billion dollars in annual sales.

  6. Combination therapy - Wikipedia

    en.wikipedia.org/wiki/Combination_therapy

    Combination therapy or polytherapy is therapy that uses more than one medication or modality. Typically, the term refers to using multiple therapies to treat a single disease, and often all the therapies are pharmaceutical (although it can also involve non-medical therapy, such as the combination of medications and talk therapy to treat depression).

  7. Upadacitinib - Wikipedia

    en.wikipedia.org/wiki/Upadacitinib

    The efficacy and safety of upadacitinib were evaluated in two randomized induction trials of 857 participants with moderately to severely active Crohn's disease, CD-1 (NCT03345836) and CD-2 (NCT03345849). [24] Participants were randomized 2:1 to receive 45 mg of upadacitinib or placebo once a day for 12 weeks. [24]

  8. 1 in 3 older Americans take aspirin daily. What does it do?

    www.aol.com/1-3-older-americans-aspirin...

    Nearly one in three Americans over the age of 60 — roughly 19 million people — take aspirin daily, according to a 2021 study in Annals of Internal Medicine.. Should you be among that group?

  9. Interleukin 31 - Wikipedia

    en.wikipedia.org/wiki/Interleukin_31

    76399 Ensembl ENSG00000204671 ENSMUSG00000029437 UniProt Q6EBC2 Q6EAL8 RefSeq (mRNA) NM_001014336 NM_029594 RefSeq (protein) NP_001014358 NP_083870 Location (UCSC) Chr 12: 122.17 – 122.17 Mb Chr 5: 123.62 – 123.63 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Interleukin-31 (IL-31) is a protein that in humans is encoded by the IL31 gene that resides on chromosome 12. IL-31 is ...

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