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  2. Single-nucleotide polymorphism - Wikipedia

    en.wikipedia.org/wiki/Single-nucleotide_polymorphism

    The upper DNA molecule differs from the lower DNA molecule at a single base-pair location (a G/A polymorphism) In genetics and bioinformatics, a single-nucleotide polymorphism (SNP / s n ɪ p /; plural SNPs / s n ɪ p s /) is a germline substitution of a single nucleotide at a specific position in the genome.

  3. SNP array - Wikipedia

    en.wikipedia.org/wiki/SNP_array

    In molecular biology, SNP array is a type of DNA microarray which is used to detect polymorphisms within a population. A single nucleotide polymorphism (SNP), a variation at a single site in DNA , is the most frequent type of variation in the genome.

  4. Tag SNP - Wikipedia

    en.wikipedia.org/wiki/Tag_SNP

    A tag SNP is a representative single nucleotide polymorphism (SNP) in a region of the genome with high linkage disequilibrium that represents a group of SNPs called a haplotype. It is possible to identify genetic variation and association to phenotypes without genotyping every SNP in a chromosomal region.

  5. Genealogical DNA test - Wikipedia

    en.wikipedia.org/wiki/Genealogical_DNA_test

    A person's haplogroup can often be inferred from their STR results, but can be proven only with a Y-chromosome SNP test (Y-SNP test). A single-nucleotide polymorphism (SNP) is a change to a single nucleotide in a DNA sequence. Typical Y-DNA SNP tests test about 20,000 to 35,000 SNPs. [34] Getting a SNP test allows a much higher resolution than ...

  6. Genome-wide association study - Wikipedia

    en.wikipedia.org/wiki/Genome-wide_association_study

    It identified two SNPs with significantly altered allele frequency between the two groups. These SNPs were located in the gene encoding complement factor H, which was an unexpected finding in the research of ARMD. The findings from these first GWA studies have subsequently prompted further functional research towards therapeutical manipulation ...

  7. SNP genotyping - Wikipedia

    en.wikipedia.org/wiki/SNP_genotyping

    SNP genotyping is the measurement of genetic variations of single nucleotide polymorphisms (SNPs) between members of a species. It is a form of genotyping , which is the measurement of more general genetic variation.

  8. Human Y-chromosome DNA haplogroup - Wikipedia

    en.wikipedia.org/wiki/Human_Y-chromosome_DNA_ha...

    Subclades are defined by a terminal SNP, the SNP furthest down in the Y-chromosome phylogenetic tree. [ 9 ] [ 10 ] The Y Chromosome Consortium (YCC) developed a system of naming major Y-DNA haplogroups with the capital letters A through T, with further subclades named using numbers and lower case letters (YCC longhand nomenclature ).

  9. Haplogroup - Wikipedia

    en.wikipedia.org/wiki/Haplogroup

    A haplotype is a group of alleles in an organism that are inherited together from a single parent, [1] [2] and a haplogroup (haploid from the Greek: ἁπλοῦς, haploûs, "onefold, simple" and English: group) is a group of similar haplotypes that share a common ancestor with a single-nucleotide polymorphism mutation. [3]