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[3] [4] It was introduced as a sedative and medication for morning sickness without having been tested on pregnant women. [5] While initially deemed to be safe in pregnancy, concerns regarding birth defects were noted in 1961, and the medication was removed from the market in Europe that year. [3] [6]
Morning sickness, also called nausea and vomiting of pregnancy (NVP), is a symptom of pregnancy that involves nausea or vomiting. [ 1 ] Despite the name, nausea or vomiting can occur at any time during the day. [ 2 ] Typically the symptoms occur between the 4th and 16th week of pregnancy. [ 2 ]
Thalidomide, sold under the brand names Contergan and Thalomid among others, is an oral medication used to treat a number of cancers (e.g., multiple myeloma), graft-versus-host disease, and many skin disorders (e.g., complications of leprosy such as skin lesions). [ 6 ][ 7 ] Thalidomide has been used to treat conditions associated with HIV ...
Pipamazine was introduced to the U.S. market in 1959 by G. D. Searle & Company. It was advertised for morning sickness [2] and postoperative nausea and vomiting, and was claimed to reduce the need for postoperative analgesia. [3] It was eventually withdrawn from the U.S. market in 1969, after reports of hepatotoxicity (liver injury). [4][5]
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Cancer induction. Cancer induction is the most significant long-term risk of exposure to a nuclear bomb. Approximately 1 out of every 80 people exposed to 1 Gray will die from cancer, in addition to the normal rate of 20 out of 80. About 1 in 40 people will get cancer, in addition to the typical rates of 16-20 out of 40.
The effects included "metallic taste, erythema, nausea, vomiting, diarrhea, hair loss, deaths of pets, farm and wild animals, and damage to plants." [16] Some local statistics showed dramatic one-year changes among the most vulnerable: "in Dauphin County, where the Three Mile Island plant is located, the 1979 death rate among infants under one ...
Carpal tunnel syndrome – Carpal tunnel syndrome can occur in up to 70% of pregnant women and typically has a benign course. [16][17] It manifests as pain, numbness, and tingling in the thumb, index finger, middle finger and the thumb side of the ring finger. [18] The symptoms of carpal tunnel syndrome during pregnancy are usually mild and do ...
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