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Helenalin, or (-)-4-Hydroxy-4a,8-dimethyl-3,3a,4a,7a,8,9,9a-octahydroazuleno[6,5-b]furan-2,5-dione, is a toxic sesquiterpene lactone which can be found in several plants such as Arnica montana and Arnica chamissonis Helenalin is responsible for the toxicity of the Arnica spp.
Arnica montana, also known as wolf's bane, leopard's bane, mountain tobacco and mountain arnica, [4] is a moderately toxic European flowering plant in the daisy family Asteraceae that has a large yellow flower head. The names "wolf's bane" and "leopard's bane" are also used for another plant, Aconitum, which is extremely poisonous.
Arnica / ˈ ɑːr n ɪ k ə / is a genus of perennial, herbaceous plants in the sunflower family ().The genus name Arnica may be derived from the Greek arni, "lamb", in reference to the plants' soft, hairy leaves.
The disease is named because it is a porphyria that often presents with skin manifestations later in life. The disorder results from low levels of the enzyme responsible for the fifth step in heme production. Heme is a vital molecule for all of the body's organs. It is a component of hemoglobin, the molecule that carries oxygen in the blood.
Keratinocytes form tight junctions with the nerves of the skin and hold the Langerhans cells and intra-dermal lymphocytes in position within the epidermis. Keratinocytes also modulate the immune system : apart from the above-mentioned antimicrobial peptides and chemokines they are also potent producers of anti-inflammatory mediators such as IL ...
This compound is formed from the breakdown of red blood cells, processed by the liver, and excreted in bile—which darkens urine. ... Your Skin or Eyes May Have a Yellow Tinge. When the liver is ...
The Human Cell Atlas project, which started in 2016, had as one of its goals to "catalog all cell types (for example, immune cells or brain cells) and sub-types in the human body". [13] By 2018, the Human Cell Atlas description based the project on the assumption that "our characterization of the hundreds of types and subtypes of cells in the ...
Through the process of radial extension, cells of the animal pole that were once several layers thick divide to form a thin layer. At the same time, when this thin layer of dividing cells reaches the dorsal lip of the blastopore, another process occurs termed convergent extension. During convergent extension, cells that approach the lip ...